ID   TRAM_AGRFC              Reviewed;         102 AA.
AC   Q44452;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Transcriptional repressor TraM;
GN   Name=traM; OrderedLocusNames=Atu6131; ORFNames=AGR_pTi_bx139;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7814335; DOI=10.1128/jb.177.2.449-458.1995;
RA   Hwang I., Cook D.M., Farrand S.K.;
RT   "A new regulatory element modulates homoserine lactone-mediated
RT   autoinduction of Ti plasmid conjugal transfer.";
RL   J. Bacteriol. 177:449-458(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- FUNCTION: Negatively regulates conjugation and the expression of tra
CC       genes by antagonizing TraR/AAI-dependent activation. TraM may either
CC       bind or modify TraR or AAI making them unavailable. Alternatively, TraM
CC       may bind tra promoters preventing TraR activation.
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DR   EMBL; AF010180; AAC17210.1; -; Genomic_DNA.
DR   EMBL; AE007871; AAK91095.1; -; Genomic_DNA.
DR   PIR; AI3243; AI3243.
DR   PIR; T03423; T03423.
DR   RefSeq; NP_396654.1; NC_003065.3.
DR   RefSeq; WP_003523843.1; NZ_AF010180.1.
DR   AlphaFoldDB; Q44452; -.
DR   SMR; Q44452; -.
DR   EnsemblBacteria; AAK91095; AAK91095; Atu6131.
DR   KEGG; atu:Atu6131; -.
DR   HOGENOM; CLU_2271418_0_0_5; -.
DR   OMA; ASIEMHA; -.
DR   BioCyc; AGRO:ATU6131-MON; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR015309; Tscrpt_rep_TraM.
DR   InterPro; IPR036336; Tscrpt_rep_TraM_sf.
DR   Pfam; PF09228; Prok-TraM; 1.
DR   PIRSF; PIRSF017930; Transcript_repress_TraM; 1.
DR   SUPFAM; SSF109631; SSF109631; 1.
PE   4: Predicted;
KW   Conjugation; Plasmid; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..102
FT                   /note="Transcriptional repressor TraM"
FT                   /id="PRO_0000065606"
SQ   SEQUENCE   102 AA;  11227 MW;  6FD02DF26C88F291 CRC64;
     MESEDATLTK KVELRPLVGL TRGLHPADLE KLTIDAIRAH RRLVEKADEL FQALPESYKS
     GKEVGGPQHL CYIEASIEMH AQMSAVSTLI SILGYIPNAT VN