TRAM_RHIRD
ID TRAM_RHIRD Reviewed; 102 AA.
AC Q57471;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Transcriptional repressor TraM;
GN Name=traM;
OS Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium
OS radiobacter).
OG Plasmid pTiA6NC.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=358;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7868612; DOI=10.1128/jb.177.5.1367-1373.1995;
RA Fuqua C., Burbea M., Winans S.C.;
RT "Activity of the Agrobacterium Ti plasmid conjugal transfer regulator TraR
RT is inhibited by the product of the traM gene.";
RL J. Bacteriol. 177:1367-1373(1995).
CC -!- FUNCTION: Negatively regulates conjugation and the expression of tra
CC genes by antagonizing TraR/AAI-dependent activation. TraM may either
CC bind or modify TraR or AAI making them unavailable. Alternatively, TraM
CC may bind tra promoters preventing TraR activation.
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DR EMBL; AF242881; AAC28120.1; -; Genomic_DNA.
DR EMBL; U16786; AAA64838.1; -; Genomic_DNA.
DR PIR; I39703; I39703.
DR RefSeq; NP_059700.1; NC_002377.1.
DR RefSeq; WP_010892388.1; NC_002377.1.
DR PDB; 1RFY; X-ray; 1.60 A; A/B=1-102.
DR PDB; 1UPG; X-ray; 1.80 A; A/B=1-102.
DR PDB; 1US6; X-ray; 1.65 A; A/B=1-102.
DR PDBsum; 1RFY; -.
DR PDBsum; 1UPG; -.
DR PDBsum; 1US6; -.
DR AlphaFoldDB; Q57471; -.
DR SMR; Q57471; -.
DR EvolutionaryTrace; Q57471; -.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR015309; Tscrpt_rep_TraM.
DR InterPro; IPR036336; Tscrpt_rep_TraM_sf.
DR Pfam; PF09228; Prok-TraM; 1.
DR PIRSF; PIRSF017930; Transcript_repress_TraM; 1.
DR SUPFAM; SSF109631; SSF109631; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Conjugation; Plasmid; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..102
FT /note="Transcriptional repressor TraM"
FT /id="PRO_0000065607"
FT STRAND 3..5
FT /evidence="ECO:0007829|PDB:1US6"
FT HELIX 16..21
FT /evidence="ECO:0007829|PDB:1RFY"
FT HELIX 26..52
FT /evidence="ECO:0007829|PDB:1RFY"
FT HELIX 56..59
FT /evidence="ECO:0007829|PDB:1RFY"
FT HELIX 67..93
FT /evidence="ECO:0007829|PDB:1RFY"
SQ SEQUENCE 102 AA; 11401 MW; 78991A239468D7A7 CRC64;
MELEDANVTK KVELRPLIGL TRGLPPTDLE TITIDAIRTH RRLVEKADEL FQALPETYKT
GQACGGPQHI RYIEASIEMH AQMSALNTLY SILGFIPKVV VN
