TRAW_ECOLI
ID TRAW_ECOLI Reviewed; 210 AA.
AC P18472;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 2.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Protein TraW;
DE Flags: Precursor;
GN Name=traW; OrderedLocusNames=ECOK12F086;
OS Escherichia coli (strain K12).
OG Plasmid F.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION, AND
RP DISRUPTION PHENOTYPE.
RC STRAIN=K12;
RX PubMed=1355084; DOI=10.1128/jb.174.17.5567-5574.1992;
RA Maneewannakul S., Maneewannakul K., Ippen-Ihler K.;
RT "Characterization, localization, and sequence of F transfer region
RT products: the pilus assembly gene product TraW and a new product, TrbI.";
RL J. Bacteriol. 174:5567-5574(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7915817; DOI=10.1128/mr.58.2.162-210.1994;
RA Frost L.S., Ippen-Ihler K., Skurray R.A.;
RT "Analysis of the sequence and gene products of the transfer region of the F
RT sex factor.";
RL Microbiol. Rev. 58:162-210(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / CR63;
RA Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.;
RT "Complete nucleotide sequence of the F plasmid: its implications for
RT organization and diversification of plasmid genomes.";
RL Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 195-210.
RC STRAIN=K12;
RX PubMed=2198250; DOI=10.1128/jb.172.8.4263-4270.1990;
RA Moore D., Maneewannakul K., Maneewannakul S., Wu J.H., Ippen-Ihler K.,
RA Bradley D.E.;
RT "Characterization of the F-plasmid conjugative transfer gene traU.";
RL J. Bacteriol. 172:4263-4270(1990).
RN [5]
RP SUBCELLULAR LOCATION.
RC STRAIN=K12; PLASMID=F;
RX PubMed=1593622; DOI=10.1016/0022-2836(92)90923-8;
RA Maneewannakul S., Kathir P., Ippen-Ihler K.;
RT "Characterization of the F plasmid mating aggregation gene traN and of a
RT new F transfer region locus trbE.";
RL J. Mol. Biol. 225:299-311(1992).
CC -!- FUNCTION: Involved in F-pilus assembly. Required for F plasmid
CC conjugative transfer. {ECO:0000305|PubMed:1355084}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000269|PubMed:1355084,
CC ECO:0000305|PubMed:1593622}.
CC -!- DISRUPTION PHENOTYPE: No F pili expressed on cell surface.
CC {ECO:0000269|PubMed:1355084}.
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DR EMBL; M93106; AAA24689.1; -; Genomic_DNA.
DR EMBL; U01159; AAC44200.1; -; Genomic_DNA.
DR EMBL; AP001918; BAA97956.1; -; Genomic_DNA.
DR EMBL; M34695; AAA98087.2; -; Genomic_DNA.
DR PIR; B42938; B42938.
DR RefSeq; NP_061465.1; NC_002483.1.
DR RefSeq; NP_862931.1; NC_004998.1.
DR RefSeq; WP_001203720.1; NZ_SSUW01000046.1.
DR RefSeq; YP_001294745.1; NC_009602.1.
DR RefSeq; YP_001711952.1; NC_010409.1.
DR RefSeq; YP_003937630.1; NC_014615.1.
DR RefSeq; YP_004870066.1; NC_016039.1.
DR RefSeq; YP_008997945.1; NC_023315.1.
DR RefSeq; YP_009070603.1; NC_025175.1.
DR AlphaFoldDB; P18472; -.
DR DIP; DIP-28103N; -.
DR PRIDE; P18472; -.
DR PATRIC; fig|83333.107.peg.626; -.
DR PRO; PR:P18472; -.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR InterPro; IPR014114; TraW.
DR InterPro; IPR025864; TraW_N_dom.
DR Pfam; PF12477; TraW_N; 1.
DR TIGRFAMs; TIGR02743; TraW; 1.
PE 3: Inferred from homology;
KW Conjugation; Periplasm; Plasmid; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..210
FT /note="Protein TraW"
FT /id="PRO_0000024510"
SQ SEQUENCE 210 AA; 23630 MW; E4D66FEC04D013C9 CRC64;
MRCRGLIALL IWGQSVAAAD LGTWGDLWPV KEPDMLTVIM QRLTALEQSG EMGRKMDAFK
ERVIRNSLRP PAVPGIGRTE KYGSRLFDPS VRLAADIRDN EGRVFARQGE VMNPLQYVPF
NQTLYFINGD DPAQVAWMKR QTPPTLESKI ILVQGSIPEM QKSLDSRVYF DQNGVLCQRL
GIDQVPARVS AVPGDRFLKV EFIPAEEGRK
