TRAY1_SALTI
ID TRAY1_SALTI Reviewed; 69 AA.
AC P12059;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=Relaxosome protein TraY;
GN Name=traY;
OS Salmonella typhi.
OG Plasmid IncFV pED208.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2877970; DOI=10.1128/jb.168.2.990-998.1986;
RA Finlay B.B., Frost L.S., Paranchych W.;
RT "Nucleotide sequence of the tra YALE region from IncFV plasmid pED208.";
RL J. Bacteriol. 168:990-998(1986).
CC -!- FUNCTION: Conjugative DNA transfer (CDT) is the unidirectional transfer
CC of ssDNA plasmid from a donor to a recipient cell. It is the central
CC mechanism by which antibiotic resistance and virulence factors are
CC propagated in bacterial populations. Part of the relaxosome, which
CC facilitates a site- and strand-specific cut in the origin of transfer
CC by TraI, at the nic site. Relaxosome formation requires binding of IHF
CC and TraY to the oriT region, which then facilitates binding of TraI (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Part of the relaxosome, a complex composed of plasmid encoded
CC TraI, TraM, TraY and host-encoded IHF bound to the F plasmid origin of
CC transfer (oriT). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TraY family. {ECO:0000305}.
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DR EMBL; M14733; AAA25604.1; -; Genomic_DNA.
DR AlphaFoldDB; P12059; -.
DR SMR; P12059; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR008876; TraY.
DR Pfam; PF05509; TraY; 1.
PE 3: Inferred from homology;
KW Conjugation; Cytoplasm; DNA-binding; Plasmid.
FT CHAIN 1..69
FT /note="Relaxosome protein TraY"
FT /id="PRO_0000068486"
SQ SEQUENCE 69 AA; 7788 MW; C600BCCC94FD278E CRC64;
MSGNIGANPI GKKVNISCSL DEAIDELLME SALKSGWSKK REAELRLEDH LRRFSLVPAE
EQYIEKKVD