ID   BUD13_CHICK             Reviewed;         559 AA.
AC   Q5ZIJ0;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=BUD13 homolog;
GN   Name=BUD13; ORFNames=RCJMB04_25m15;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in pre-mRNA splicing as component of the activated
CC       spliceosome. {ECO:0000250|UniProtKB:Q9BRD0}.
CC   -!- SUBUNIT: Part of the activated spliceosome B/catalytic step 1
CC       spliceosome, one of the forms of the spliceosome which has a well-
CC       formed active site but still cannot catalyze the branching reaction and
CC       is composed of at least 52 proteins, the U2, U5 and U6 snRNAs and the
CC       pre-mRNA. {ECO:0000250|UniProtKB:Q9BRD0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BRD0}.
CC   -!- SIMILARITY: Belongs to the CWC26 family. {ECO:0000305}.
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DR   EMBL; AJ720794; CAG32453.1; -; mRNA.
DR   RefSeq; NP_001034408.1; NM_001039319.2.
DR   AlphaFoldDB; Q5ZIJ0; -.
DR   STRING; 9031.ENSGALP00000011403; -.
DR   PaxDb; Q5ZIJ0; -.
DR   GeneID; 428248; -.
DR   KEGG; gga:428248; -.
DR   CTD; 84811; -.
DR   VEuPathDB; HostDB:geneid_428248; -.
DR   eggNOG; KOG2654; Eukaryota.
DR   InParanoid; Q5ZIJ0; -.
DR   OrthoDB; 1558074at2759; -.
DR   PhylomeDB; Q5ZIJ0; -.
DR   PRO; PR:Q5ZIJ0; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0070274; C:RES complex; IBA:GO_Central.
DR   GO; GO:0071005; C:U2-type precatalytic spliceosome; ISS:UniProtKB.
DR   GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR018609; Bud13.
DR   Pfam; PF09736; Bud13; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..559
FT                   /note="BUD13 homolog"
FT                   /id="PRO_0000287691"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          89..456
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          373..431
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        89..107
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        119..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..276
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..306
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        340..355
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        376..436
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..506
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  64409 MW;  1388DCCF70CB3A0F CRC64;
     MAAQGVSKAQ YLQRYLSGPP AAQPRRRRKK KLPSGSGRAG MRIVDDDVGW SSIAAVPEKE
     EEEDEGDMPV VAEFIDERPD EVKLMEEFRT NSKWKLLGDR DEDSPSSDVS VPAKATTRQQ
     RHDSPDNSPP RRVRHDSPDL SPPRQERNNS ASLLPRKERQ HGSPDLSPPR RKRHDSPDLS
     PPRRKRHDDS PDLSPPRRKR HDSPDLSPPR RKRHDSPDLS PPRRQRHDSP DPSPPRKKRH
     DSPDLSPQEQ QTTPDLSLQR KKRYDSDPDS SPSLRKRARS PGHKKPSRTK DASPVKKLRR
     DSDSPPPRRG TQNASEADLS PQGKNHRALP SGKGQHGSKS PPDLSRHHYP DDKGSPKKGN
     MMSGVRAGLV SADVLRREQQ ELRKQERSSK HLEEESRHTE TIFRDKSGRK RDLVQERLEQ
     QQKDEAKSER DEQYARWGRG LAQGRQQQQN VEDAIKEMQK PLARYIDDED LDRMLREQER
     EGDPMAEFIR KRKAKESKEK KEKPRYSGPA PPLNRFNIWP GHRWDGVDRS NGFEQQFFAR
     MANKKAVQEL AYKWSIEDM