ID   TRBC_ECOLI              Reviewed;         212 AA.
AC   P18473;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Periplasmic protein TrbC;
DE   Flags: Precursor;
GN   Name=trbC; OrderedLocusNames=ECOK12F088;
OS   Escherichia coli (strain K12).
OG   Plasmid F.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2050638; DOI=10.1128/jb.173.12.3872-3878.1991;
RA   Maneewannakul S., Maneewannakul K., Ippen-Ihler K.;
RT   "Characterization of trbC, a new F plasmid tra operon gene that is
RT   essential to conjugative transfer.";
RL   J. Bacteriol. 173:3872-3878(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7915817; DOI=10.1128/mr.58.2.162-210.1994;
RA   Frost L.S., Ippen-Ihler K., Skurray R.A.;
RT   "Analysis of the sequence and gene products of the transfer region of the F
RT   sex factor.";
RL   Microbiol. Rev. 58:162-210(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / CR63;
RA   Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.;
RT   "Complete nucleotide sequence of the F plasmid: its implications for
RT   organization and diversification of plasmid genomes.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-11.
RC   STRAIN=K12;
RX   PubMed=2198250; DOI=10.1128/jb.172.8.4263-4270.1990;
RA   Moore D., Maneewannakul K., Maneewannakul S., Wu J.H., Ippen-Ihler K.,
RA   Bradley D.E.;
RT   "Characterization of the F-plasmid conjugative transfer gene traU.";
RL   J. Bacteriol. 172:4263-4270(1990).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 170-212, AND SUBCELLULAR LOCATION.
RC   STRAIN=K12; PLASMID=F;
RX   PubMed=1593622; DOI=10.1016/0022-2836(92)90923-8;
RA   Maneewannakul S., Kathir P., Ippen-Ihler K.;
RT   "Characterization of the F plasmid mating aggregation gene traN and of a
RT   new F transfer region locus trbE.";
RL   J. Mol. Biol. 225:299-311(1992).
CC   -!- FUNCTION: Essential for F plasmid conjugative transfer, participates in
CC       F-pilus assembly.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305|PubMed:1593622}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-5 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; M60427; AAA24914.1; -; Genomic_DNA.
DR   EMBL; U01159; AAC44205.1; -; Genomic_DNA.
DR   EMBL; AP001918; BAA97958.1; -; Genomic_DNA.
DR   EMBL; M34695; AAA98089.1; -; Genomic_DNA.
DR   EMBL; X61575; CAA43774.1; -; Genomic_DNA.
DR   PIR; A39442; A39442.
DR   RefSeq; NP_061467.1; NC_002483.1.
DR   RefSeq; WP_000777688.1; NZ_CP014273.1.
DR   RefSeq; YP_009060143.1; NC_024956.1.
DR   RefSeq; YP_009070601.1; NC_025175.1.
DR   AlphaFoldDB; P18473; -.
DR   SMR; P18473; -.
DR   PRIDE; P18473; -.
DR   PATRIC; fig|83333.107.peg.624; -.
DR   PRO; PR:P18473; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019106; T4SS_TrbC.
DR   InterPro; IPR014113; T4SS_TrbC_subgr.
DR   Pfam; PF09673; TrbC_Ftype; 1.
DR   TIGRFAMs; TIGR02742; TrbC_Ftype; 1.
PE   4: Predicted;
KW   Conjugation; Periplasm; Plasmid; Signal.
FT   SIGNAL          1..21
FT   CHAIN           22..212
FT                   /note="Periplasmic protein TrbC"
FT                   /id="PRO_0000024512"
SQ   SEQUENCE   212 AA;  23433 MW;  57A4BB76634B4598 CRC64;
     MKLSMKSLAA LLMMLNGAVM ASENVNTPEN RQFLKQQENL SRQLREKPDH QLKAWAEKQV
     LENPLQRSDN HFLDELVRKQ QASQDGKPRQ GALYFVSFSI PEEGLKRMLG ETRHFGIPAT
     LRGMVNNDLK TTAEAVLSLV KDGATDGVQI DPTLFSQYGI RTVPALVVFC SQGYDIIRGN
     LRVGQALEKV AATGDCRQVA HDLLAGKGDS GK