ID   TRCG1_MOUSE             Reviewed;         825 AA.
AC   Q58Y74; Q58Y73;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Taste receptor cell protein 1;
DE            Short=Taste receptor protein 1;
DE   Flags: Precursor;
GN   Name=Trcg1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND TISSUE SPECIFICITY.
RC   STRAIN=C57BL/6J;
RX   PubMed=15780750; DOI=10.1016/j.ygeno.2004.12.005;
RA   LopezJimenez N.D., Sainz E.S., Cavenagh M.M., Cruz-Ithier M.A.,
RA   Blackwood C.A., Battey J.F., Sullivan S.L.;
RT   "Two novel genes, Gpr113, which encodes a family 2 G-protein-coupled
RT   receptor, and Trcg1, are selectively expressed in taste receptor cells.";
RL   Genomics 85:472-482(2005).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q58Y74-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q58Y74-2; Sequence=VSP_029241, VSP_029242, VSP_029243;
CC   -!- TISSUE SPECIFICITY: Expression is restricted to circumvallate papillae.
CC       {ECO:0000269|PubMed:15780750}.
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DR   EMBL; AY701870; AAW23328.1; -; mRNA.
DR   EMBL; AY701871; AAW23329.1; -; mRNA.
DR   CCDS; CCDS23218.1; -. [Q58Y74-1]
DR   RefSeq; NP_001014420.2; NM_001014398.2.
DR   AlphaFoldDB; Q58Y74; -.
DR   SMR; Q58Y74; -.
DR   STRING; 10090.ENSMUSP00000091357; -.
DR   iPTMnet; Q58Y74; -.
DR   PhosphoSitePlus; Q58Y74; -.
DR   PaxDb; Q58Y74; -.
DR   PRIDE; Q58Y74; -.
DR   DNASU; 541610; -.
DR   GeneID; 541610; -.
DR   KEGG; mmu:541610; -.
DR   UCSC; uc009pup.1; mouse. [Q58Y74-2]
DR   CTD; 541610; -.
DR   MGI; MGI:3576664; Trcg1.
DR   eggNOG; KOG4208; Eukaryota.
DR   InParanoid; Q58Y74; -.
DR   OrthoDB; 528085at2759; -.
DR   PhylomeDB; Q58Y74; -.
DR   BioGRID-ORCS; 541610; 0 hits in 72 CRISPR screens.
DR   PRO; PR:Q58Y74; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q58Y74; protein.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..825
FT                   /note="Taste receptor cell protein 1"
FT                   /id="PRO_0000309591"
FT   REGION          66..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          299..322
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..560
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15780750"
FT                   /id="VSP_029241"
FT   VAR_SEQ         731..769
FT                   /note="HQEPLTARVQTAFFGAVPAQAIIQDTVLQALGSLQETEG -> QHPQLQSLK
FT                   RPQGRGHAEPPALHFSLCPGGSLYGSSLHQ (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15780750"
FT                   /id="VSP_029242"
FT   VAR_SEQ         770..825
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15780750"
FT                   /id="VSP_029243"
FT   CONFLICT        590
FT                   /note="S -> P (in Ref. 1; AAW23329)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        726
FT                   /note="V -> A (in Ref. 1; AAW23329)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   825 AA;  88916 MW;  93292101649775E1 CRC64;
     MDKQWFPAAG ILLAALLVVS ASTLTLLSTN EDPEQFPSAP GTSAQQSSRI LLGILTDVTG
     GINSVEREPE ALGRRAGGLS TEGAGGQESP SMPGPSGRVI PEPIPSALTT SASDMASQPV
     SSGADPIEEI MALGTLETIT MSSPQPSPRH ESEQKFDKVF RLCGTVPASE TLEKNVASKP
     AWHLIKAPPP PIFSRSPHLL WCTPNSTVYI PVPAWRDGHS RPEASSSVPL APSTSLGLPI
     FPWMPNILKA TESLLPASPG RSGLDLTSQV GSRASENTVA LDTGPVSRGT SVLLLPSATS
     PSQASSLHSP RPSSASPLSA SPSPAALSFF PSPASILVLV SSVTTGASDS PKAPVSVIAP
     STTDSFIKTS NLGPQIALQP SHPGLWLPTS PIHMPTLSLQ HFSSPPSTAH SSGFTESSVH
     ADPTLASTLP HPGQDMSLQD LSFSTGGRSH TTHSVTFRIN SNRFTKAVWN LVPLERWLLN
     RLICYQLRFI YQEAFPNFRN VSTLLFRPGC PEVKASLIFG PPDPSSIEIL WTLYRKVKSS
     RWSLGYLSLA DHGLSSAGYS MTDLTQEIIN ISFTLMRPFL PQLLLPSSQS CILLEKQTIQ
     LVTHEVSRFY KAELQSQPLL LFSNVKEWVS VYMEYKFKSP IPIRLQGLAS HLAHHITDPT
     LQKSSIMANG EKADLVFYEM WLLILGHPFT KTLENKTSSE CQELRGLLTR QLTSVLQPLK
     NFGQVVVEEF HQEPLTARVQ TAFFGAVPAQ AIIQDTVLQA LGSLQETEGL QLEMLLPVLG
     TPSSRASRGP RGGAMLNLQR FTSLFVLVAL CTAPPFINKQ ALYLS