BUD25_YEAST
ID BUD25_YEAST Reviewed; 153 AA.
AC P85052; D3DLR2;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Bud site selection protein 25;
GN Name=BUD25 {ECO:0000312|SGD:S000007590}; OrderedLocusNames=YER014C-A;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1] {ECO:0000312|SGD:S000007590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3] {ECO:0000305}
RP FUNCTION.
RX PubMed=11452010; DOI=10.1091/mbc.12.7.2147;
RA Ni L., Snyder M.;
RT "A genomic study of the bipolar bud site selection pattern in Saccharomyces
RT cerevisiae.";
RL Mol. Biol. Cell 12:2147-2170(2001).
RN [4] {ECO:0000305}
RP FUNCTION IN MMS RESISTANCE.
RX PubMed=12482937; DOI=10.1073/pnas.262669299;
RA Chang M., Bellaoui M., Boone C., Brown G.W.;
RT "A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals
RT genes required for S phase progression in the presence of DNA damage.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:16934-16939(2002).
CC -!- FUNCTION: Involved in bud site selection. Required for resistance to
CC the DNA-damaging agent methyl methanesulfonate (MMS).
CC {ECO:0000269|PubMed:11452010, ECO:0000269|PubMed:12482937}.
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DR EMBL; U18778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BK006939; DAA07666.1; -; Genomic_DNA.
DR RefSeq; NP_076437.1; NM_001184456.1.
DR AlphaFoldDB; P85052; -.
DR BioGRID; 36748; 80.
DR STRING; 4932.YER014C-A; -.
DR PaxDb; P85052; -.
DR EnsemblFungi; YER014C-A_mRNA; YER014C-A; YER014C-A.
DR GeneID; 856735; -.
DR KEGG; sce:YER014C-A; -.
DR SGD; S000007590; BUD25.
DR VEuPathDB; FungiDB:YER014C-A; -.
DR HOGENOM; CLU_1714738_0_0_1; -.
DR BioCyc; YEAST:G3O-30391-MON; -.
DR PRO; PR:P85052; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P85052; protein.
DR GO; GO:0000282; P:cellular bud site selection; HMP:SGD.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW DNA damage; Reference proteome.
FT CHAIN 1..153
FT /note="Bud site selection protein 25"
FT /id="PRO_0000270625"
SQ SEQUENCE 153 AA; 18006 MW; B3BF954BA56FC43C CRC64;
MFCTWDSWDT GTSRKSHSPH RNCLAVRFLQ LPFSSFLPCV ITYMKSWQTS IGDSEFPLTS
FQILVTDAEV VVQRIFDCIN GYLPGWHYRN TVFIEHTTSY HRSHFCIFVE GVWVCGEFVK
KWFEIPFDNR IENYTKQFPW ILIGFGNQVS KAL
