ID   TRF1_KLULA              Reviewed;         103 AA.
AC   P05476;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=DNA-binding protein TRF1;
DE   AltName: Full=Terminal region recognition factor 1;
GN   Name=TRF1;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OG   Plasmid pGKl-2.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=3041369; DOI=10.1093/nar/16.13.5863;
RA   Tommasino M., Ricci S., Galeotti C.L.;
RT   "Genome organization of the killer plasmid pGKL2 from Kluyveromyces
RT   lactis.";
RL   Nucleic Acids Res. 16:5863-5878(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=3138657;
RA   Wilson D.W., Meacock P.A.;
RT   "Extranuclear gene expression in yeast: evidence for a plasmid-encoded RNA
RT   polymerase of unique structure.";
RL   Nucleic Acids Res. 16:8097-8112(1988).
RN   [3]
RP   FUNCTION.
RX   PubMed=1882549; DOI=10.1002/yea.320070306;
RA   Tommasino M.;
RT   "Killer system of Kluyveromyces lactis: the open reading frame 10 of the
RT   pGKL2 plasmid encodes a putative DNA binding protein.";
RL   Yeast 7:245-252(1991).
RN   [4]
RP   FUNCTION.
RX   PubMed=1763054; DOI=10.1073/pnas.88.24.11398;
RA   McNeel D.G., Tamanoi F.;
RT   "Terminal region recognition factor 1, a DNA-binding protein recognizing
RT   the inverted terminal repeats of the pGKl linear DNA plasmids.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:11398-11402(1991).
CC   -!- FUNCTION: DNA-binding protein that recognizes the inverted terminal
CC       repeats of the pGKl linear DNA plasmids. {ECO:0000269|PubMed:1763054,
CC       ECO:0000269|PubMed:1882549}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X07776; CAA30611.1; -; Genomic_DNA.
DR   EMBL; X07946; CAA30767.1; -; Genomic_DNA.
DR   PIR; S00968; TRVKG1.
DR   AlphaFoldDB; P05476; -.
DR   SMR; P05476; -.
DR   InParanoid; P05476; -.
DR   Proteomes; UP000000598; Plasmid pGKL2.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   DNA-binding; Plasmid; Reference proteome.
FT   CHAIN           1..103
FT                   /note="DNA-binding protein TRF1"
FT                   /id="PRO_0000065628"
SQ   SEQUENCE   103 AA;  12061 MW;  45364E62E657204B CRC64;
     MANKQAEKLI TAIKKDYLKE IIKKIEELDI DKKDYIVEKL KEEKPKKKRN APKIPLNKQC
     TKETASKGKC TVAACYNHIC WAHMNKTQRN EYRLLKSVDI KTI