BUD31_DANRE
ID BUD31_DANRE Reviewed; 144 AA.
AC Q567Z7; Q6DRN2;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Protein BUD31 homolog;
DE AltName: Full=Protein G10 homolog;
GN Name=bud31; ORFNames=zgc:110615;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA Hopkins N.;
RT "Identification of 315 genes essential for early zebrafish development.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in pre-mRNA splicing process.
CC {ECO:0000250|UniProtKB:P41223}.
CC -!- SUBUNIT: Identified in the spliceosome C complex.
CC {ECO:0000250|UniProtKB:P41223}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P41223}.
CC -!- SIMILARITY: Belongs to the BUD31 (G10) family. {ECO:0000305}.
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DR EMBL; AY648727; AAT68045.1; -; mRNA.
DR EMBL; BC092952; AAH92952.1; -; mRNA.
DR RefSeq; NP_001003860.1; NM_001003860.1.
DR AlphaFoldDB; Q567Z7; -.
DR SMR; Q567Z7; -.
DR STRING; 7955.ENSDARP00000015461; -.
DR PaxDb; Q567Z7; -.
DR GeneID; 445383; -.
DR KEGG; dre:445383; -.
DR CTD; 8896; -.
DR ZFIN; ZDB-GENE-040720-3; bud31.
DR eggNOG; KOG3404; Eukaryota.
DR InParanoid; Q567Z7; -.
DR OrthoDB; 1236198at2759; -.
DR PhylomeDB; Q567Z7; -.
DR TreeFam; TF105609; -.
DR Reactome; R-DRE-72163; mRNA Splicing - Major Pathway.
DR PRO; PR:Q567Z7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR InterPro; IPR018230; BUD31/G10-rel_CS.
DR InterPro; IPR001748; G10.
DR PANTHER; PTHR19411; PTHR19411; 1.
DR Pfam; PF01125; G10; 1.
DR PRINTS; PR00322; G10.
DR PROSITE; PS00997; G10_1; 1.
DR PROSITE; PS00998; G10_2; 1.
PE 2: Evidence at transcript level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT CHAIN 1..144
FT /note="Protein BUD31 homolog"
FT /id="PRO_0000223628"
FT MOTIF 2..10
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT CONFLICT 18
FT /note="V -> I (in Ref. 1; AAT68045)"
FT /evidence="ECO:0000305"
FT CONFLICT 76
FT /note="K -> E (in Ref. 1; AAT68045)"
FT /evidence="ECO:0000305"
FT CONFLICT 81
FT /note="G -> E (in Ref. 1; AAT68045)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 144 AA; 16951 MW; 1586D5961000674C CRC64;
MPKVKRSRKP PPDGWELVEP TLDELDQKMR EAETEPHEGK RKVESLWPIF RLHHQRSRYI
FDLFYKRKAI SRELYKYCIR GGYADKNLIA KWKKQGYENL CCLRCIQTRD TNFGTNCICR
VPKGKLEVGR IIECTHCGCR GCSG