TRG_CUPNH
ID TRG_CUPNH Reviewed; 231 AA.
AC Q07259; Q0KDV8;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Putative transglycosylase H16_A0665;
DE EC=2.4.2.-;
GN OrderedLocusNames=H16_A0665;
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-207.
RX PubMed=8405966; DOI=10.1111/j.1574-6968.1993.tb06453.x;
RA Jendrossek D., Kratzin H.D., Steinbuechel A.;
RT "The Alcaligenes eutrophus ldh structural gene encodes a novel type of
RT lactate dehydrogenase.";
RL FEMS Microbiol. Lett. 112:229-235(1993).
CC -!- FUNCTION: Cell wall formation.
CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC -!- SUBCELLULAR LOCATION: Secreted. Membrane {ECO:0000305}. Note=Membrane-
CC associated. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 51 family.
CC {ECO:0000305}.
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DR EMBL; AM260479; CAJ91813.1; -; Genomic_DNA.
DR EMBL; Z22737; CAA80433.1; -; Genomic_DNA.
DR PIR; I39536; I39536.
DR RefSeq; WP_010811523.1; NZ_CP039287.1.
DR AlphaFoldDB; Q07259; -.
DR SMR; Q07259; -.
DR STRING; 381666.H16_A0665; -.
DR CAZy; GT51; Glycosyltransferase Family 51.
DR EnsemblBacteria; CAJ91813; CAJ91813; H16_A0665.
DR GeneID; 57642761; -.
DR KEGG; reh:H16_A0665; -.
DR eggNOG; COG5009; Bacteria.
DR HOGENOM; CLU_006354_1_2_4; -.
DR OMA; DERFYVH; -.
DR OrthoDB; 1793788at2; -.
DR UniPathway; UPA00219; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3810.10; -; 1.
DR InterPro; IPR001264; Glyco_trans_51.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR036950; PBP_transglycosylase.
DR Pfam; PF00912; Transgly; 1.
DR SUPFAM; SSF53955; SSF53955; 1.
PE 3: Inferred from homology;
KW Cell shape; Cell wall biogenesis/degradation; Membrane;
KW Peptidoglycan synthesis; Reference proteome; Secreted; Transferase;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..231
FT /note="Putative transglycosylase H16_A0665"
FT /id="PRO_0000083163"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 183
FT /note="P -> G (in Ref. 2; CAA80433)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 231 AA; 25806 MW; 88A2480299341D92 CRC64;
MKRLWSAFIK LLVLAVIGGA LLAAIAILAA NRQLPSLDAL TAFRHTPDYV PIGKIPRELT
GAVVAIEDER FYVHDGIDYI GVVRAGVANL SDELSQGAST ITMQVARNFY LSRDKTYTRK
LYEVLLSYRI EKALTKDEIL ELYMNKIYLG QGAYGFADAA RTYFGKRLDQ LTLAECAMLA
GLPKAPSANN PVANPRRARQ RQVYILQRML ELGRISRGEY DGALLEPLRL R
