TRH10_ARATH
ID TRH10_ARATH Reviewed; 154 AA.
AC Q9LXZ8; A0A1I9LMG8;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Putative thioredoxin H10;
DE Short=AtTrxh10;
GN OrderedLocusNames=At3g56420; ORFNames=T5P19.70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825616; DOI=10.1093/mp/ssn076;
RA Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.;
RT "Comparative genomic study of the thioredoxin family in photosynthetic
RT organisms with emphasis on Populus trichocarpa.";
RL Mol. Plant 2:308-322(2009).
CC -!- FUNCTION: Probable thiol-disulfide oxidoreductase that may be involved
CC in the redox regulation of a number of cytosolic enzymes.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
CC -!- CAUTION: The active site contains a CVPC motif wich differs from the
CC conserved CGPC motif. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB88045.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL163972; CAB88045.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE79520.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM63775.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM63776.1; -; Genomic_DNA.
DR PIR; T49043; T49043.
DR RefSeq; NP_001325846.1; NM_001339795.1.
DR RefSeq; NP_001325847.1; NM_001339794.1.
DR RefSeq; NP_191201.4; NM_115500.4.
DR AlphaFoldDB; Q9LXZ8; -.
DR SMR; Q9LXZ8; -.
DR STRING; 3702.AT3G56420.1; -.
DR PaxDb; Q9LXZ8; -.
DR PRIDE; Q9LXZ8; -.
DR ProteomicsDB; 228306; -.
DR EnsemblPlants; AT3G56420.1; AT3G56420.1; AT3G56420.
DR EnsemblPlants; AT3G56420.2; AT3G56420.2; AT3G56420.
DR EnsemblPlants; AT3G56420.3; AT3G56420.3; AT3G56420.
DR GeneID; 824809; -.
DR Gramene; AT3G56420.1; AT3G56420.1; AT3G56420.
DR Gramene; AT3G56420.2; AT3G56420.2; AT3G56420.
DR Gramene; AT3G56420.3; AT3G56420.3; AT3G56420.
DR KEGG; ath:AT3G56420; -.
DR Araport; AT3G56420; -.
DR TAIR; locus:2102579; AT3G56420.
DR eggNOG; KOG0907; Eukaryota.
DR HOGENOM; CLU_090389_14_1_1; -.
DR InParanoid; Q9LXZ8; -.
DR OMA; NICLVTS; -.
DR OrthoDB; 1482186at2759; -.
DR PhylomeDB; Q9LXZ8; -.
DR PRO; PR:Q9LXZ8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LXZ8; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Disulfide bond; Electron transport; Redox-active center;
KW Reference proteome; Transport.
FT CHAIN 1..154
FT /note="Putative thioredoxin H10"
FT /id="PRO_0000394536"
FT DOMAIN 24..148
FT /note="Thioredoxin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT ACT_SITE 74
FT /note="Nucleophile"
FT /evidence="ECO:0000255"
FT ACT_SITE 77
FT /note="Nucleophile"
FT /evidence="ECO:0000255"
FT DISULFID 74..77
FT /note="Redox-active"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ SEQUENCE 154 AA; 17371 MW; A4555699858F59DA CRC64;
MGNRCARTSC CRKLWSCICC CSNNNNNSYG QTRSQHGSKG KVHPVSRIEK WEEKITEANN
HGKILVVNFS APWCVPCKKI EPVFRDLASR YPSMIFVTVD VEELAEFSNE WNVEATPTVV
FLKDGRQMDK LVGAETSELQ KKTAAAADLF LRKP
