ID   TRHBN_MYCPA             Reviewed;         136 AA.
AC   Q740T9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Group 1 truncated hemoglobin GlbN;
DE            Short=Truncated hemoglobin;
DE            Short=trHbN;
DE   AltName: Full=Hemoglobin-like protein HbN;
GN   Name=glbN; OrderedLocusNames=MAP_1253c;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Binds oxygen cooperatively with very high affinity because of
CC       a fast combination and a slow dissociation rate. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC       Note=Binds 1 heme group per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the truncated hemoglobin family. Group I
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AE016958; AAS03570.1; -; Genomic_DNA.
DR   RefSeq; WP_010949133.1; NC_002944.2.
DR   AlphaFoldDB; Q740T9; -.
DR   SMR; Q740T9; -.
DR   STRING; 262316.MAP_1253c; -.
DR   EnsemblBacteria; AAS03570; AAS03570; MAP_1253c.
DR   KEGG; mpa:MAP_1253c; -.
DR   PATRIC; fig|262316.17.peg.1317; -.
DR   eggNOG; COG2346; Bacteria.
DR   HOGENOM; CLU_103526_2_1_11; -.
DR   OMA; HQTQFIS; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR019795; Globin_bac-like_CS.
DR   InterPro; IPR001486; Hemoglobin_trunc.
DR   InterPro; IPR016339; Hemoglobin_trunc_I.
DR   Pfam; PF01152; Bac_globin; 1.
DR   PIRSF; PIRSF002030; Globin_Protozoa/Cyanobacteria; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01213; GLOBIN_FAM_2; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Oxygen transport; Reference proteome; Transport.
FT   CHAIN           1..136
FT                   /note="Group 1 truncated hemoglobin GlbN"
FT                   /id="PRO_0000162638"
FT   BINDING         81
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   136 AA;  14410 MW;  60F09B782E945877 CRC64;
     MKILARFRKA EPASIYDRIG GHEALEVVVE NFYVRVLADE QLSGFFTGTN MNRLKGKQVE
     FFAAALGGPH PYTGAPMKQV HQGRGITMHH FGLVAGHLAD ALTAAGVPSE TVSEILGAIA
     PLAPEIATGE AGKVTV