ID   TRHBN_TETPY             Reviewed;         121 AA.
AC   P17724;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Group 1 truncated hemoglobin;
DE            Short=Truncated Hb;
DE   AltName: Full=Hemoglobin;
DE   AltName: Full=Myoglobin;
OS   Tetrahymena pyriformis.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=5908;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8485156; DOI=10.1016/0167-4781(93)90245-9;
RA   Takagi T., Iwaasa H., Yuasa H., Shikama K., Takemasa T., Watanabe Y.;
RT   "Primary structure of Tetrahymena hemoglobins.";
RL   Biochim. Biophys. Acta 1173:75-78(1993).
RN   [2]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT MET-1.
RX   PubMed=2111321; DOI=10.1016/s0021-9258(19)38930-6;
RA   Iwaasa H., Takagi T., Shikama K.;
RT   "Protozoan hemoglobin from Tetrahymena pyriformis. Isolation,
RT   characterization, and amino acid sequence.";
RL   J. Biol. Chem. 265:8603-8609(1990).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC       Note=Binds 1 heme group per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the truncated hemoglobin family. Group I
CC       subfamily. {ECO:0000305}.
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DR   EMBL; D13920; BAA03015.1; -; mRNA.
DR   PIR; S32555; A36270.
DR   PDB; 3AQ5; X-ray; 1.78 A; A/B=1-121.
DR   PDB; 3AQ6; X-ray; 1.93 A; A/B=1-121.
DR   PDB; 3AQ7; X-ray; 1.77 A; A/B=1-121.
DR   PDB; 3AQ8; X-ray; 1.83 A; A/B=1-121.
DR   PDB; 3AQ9; X-ray; 1.74 A; A/B=1-121.
DR   PDBsum; 3AQ5; -.
DR   PDBsum; 3AQ6; -.
DR   PDBsum; 3AQ7; -.
DR   PDBsum; 3AQ8; -.
DR   PDBsum; 3AQ9; -.
DR   AlphaFoldDB; P17724; -.
DR   SMR; P17724; -.
DR   iPTMnet; P17724; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR019795; Globin_bac-like_CS.
DR   InterPro; IPR001486; Hemoglobin_trunc.
DR   InterPro; IPR016339; Hemoglobin_trunc_I.
DR   Pfam; PF01152; Bac_globin; 1.
DR   PIRSF; PIRSF002030; Globin_Protozoa/Cyanobacteria; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01213; GLOBIN_FAM_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Direct protein sequencing; Heme; Iron;
KW   Metal-binding; Oxygen transport; Transport.
FT   CHAIN           1..121
FT                   /note="Group 1 truncated hemoglobin"
FT                   /id="PRO_0000162649"
FT   BINDING         73
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000305|PubMed:2111321"
FT   HELIX           7..11
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           13..28
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   TURN            32..34
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           35..38
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           43..57
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           69..72
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   TURN            73..75
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           80..96
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           101..112
FT                   /evidence="ECO:0007829|PDB:3AQ9"
FT   HELIX           115..118
FT                   /evidence="ECO:0007829|PDB:3AQ9"
SQ   SEQUENCE   121 AA;  13684 MW;  6D02948060CA2A5E CRC64;
     MNKPQTIYEK LGGENAMKAA VPLFYKKVLA DERVKHFFKN TDMDHQTKQQ TDFLTMLLGG
     PNHYKGKNMT EAHKGMNLQN LHFDAIIENL AATLKELGVT DAVINEAAKV IEHTRKDMLG
     K