ID   BUD3_SCHOC              Reviewed;         450 AA.
AC   P48012;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   11-DEC-2019, entry version 53.
DE   RecName: Full=Bud site selection protein 3;
DE   Flags: Fragment;
GN   Name=BUD3;
OS   Schwanniomyces occidentalis (Yeast) (Debaryomyces occidentalis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Schwanniomyces.
OX   NCBI_TaxID=27300;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 26077 / R91;
RX   PubMed=7597851; DOI=10.1002/yea.320110510;
RA   Iserentant D., Verachtert H.;
RT   "Cloning and sequencing of the LEU2 homologue gene of Schwanniomyces
RT   occidentalis.";
RL   Yeast 11:467-473(1995).
CC   -!- FUNCTION: Co-assembles with BUD4 at bud sites. BUD4 and BUD3 may
CC       cooperate to recognize a spatial landmark (the neck filaments) during
CC       mitosis and they subsequently become a landmark for establishing the
CC       axial budding pattern in G1 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BUD3 family. {ECO:0000305}.
CC   -!- CAUTION: Was originally thought to be 3-isopropylmalate dehydrogenase
CC       (LEU2). {ECO:0000305|PubMed:7597851}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA56224.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAA56224.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; X79823; CAA56224.1; ALT_SEQ; Genomic_DNA.
DR   PIR; S55845; S55845.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; SSF48065; 1.
PE   3: Inferred from homology;
KW   Cell cycle.
FT   CHAIN           <1..>450
FT                   /note="Bud site selection protein 3"
FT                   /id="PRO_0000066291"
FT   NON_TER         1
FT   NON_TER         450
SQ   SEQUENCE   450 AA;  51978 MW;  24CEBCBC28015B1E CRC64;
     DPLLEYSXEA MEISYTAPNS STYEPPQIRN NQLIDTILNE LLNVQTNYTM GLVNLLQNFI
     IPLRIQVLST GIGSDMTRIN QVFPPTIDEI TRINCILHDS LNKVSRYGYV EIIRVVGMIL
     PYFYKAFIRH EANLKLYTTR LNKFYSKNSK TIFSNNLINK GNYSTREIDS IVSGSLLELP
     KFKLILKRLH DAIESEKLKK KNFENFVDNE TSIITYYYNT AIEVIDAFGG CQGSEDRKID
     SQLRVFTPTG KILTELATKW PPELQYGWLS RKVVGIYELR NVKPKSFFDL EILIIFSDHL
     LFLTIIEESY YIRKKNEPIK SLSVSDILMH SLVNEKPLPV LSLLPSMEVN SWCNLNEVIT
     SCYLGVSSHT SSKQDFLRFL NVSKSGFKSX XLDHLIFTKN YEILRSKENK YLSGHKIIEL
     INKAKVLYKN QLFHLFRSTD SKITYLLNCS