ID   BUDR_KLEAE              Reviewed;         143 AA.
AC   P52665;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=HTH-type transcriptional regulator BudR;
DE   AltName: Full=Bud operon transcriptional regulator;
DE   Flags: Fragment;
GN   Name=budR;
OS   Klebsiella aerogenes (Enterobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3278689; DOI=10.1128/aem.54.1.38-42.1988;
RA   Sone H., Fujii T., Kondo K., Shimizu F., Tanaka J., Inoue T.;
RT   "Nucleotide sequence and expression of the Enterobacter aerogenes alpha-
RT   acetolactate decarboxylase gene in brewer's yeast.";
RL   Appl. Environ. Microbiol. 54:38-42(1988).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=7920643; DOI=10.1038/ng0694-205;
RA   Robison K., Gilbert W., Church G.M.;
RT   "Large scale bacterial gene discovery by similarity search.";
RL   Nat. Genet. 7:205-214(1994).
CC   -!- FUNCTION: Regulator of the budABC operon for 2,3-butanediol synthesis.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; J03433; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P52665; -.
DR   SMR; P52665; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..>143
FT                   /note="HTH-type transcriptional regulator BudR"
FT                   /id="PRO_0000105597"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   NON_TER         143
SQ   SEQUENCE   143 AA;  15890 MW;  74C617FBC4F80688 CRC64;
     MELRYLRYFV AVARERHFTR AAKALGISQP PLSQQIKRLE EEVGTPLFRR LTRGVELTEA
     GEAFYEDACK ILALSDAALE KARGIARGLN GNLSIGITSS DAFHPKIFAL IRQFQVQNMA
     VQVHQVEANM SSLTAMLAEG ELD