ID   BUGT_BORPE              Reviewed;         326 AA.
AC   Q45389; Q847Y2;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2003, sequence version 2.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Protein BugT;
DE   Flags: Precursor;
GN   Name=bugT; OrderedLocusNames=BP3782;
OS   Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257313;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11111902; DOI=10.1016/s1438-4221(00)80026-0;
RA   Antoine R., Raze D., Locht C.;
RT   "Genomics of Bordetella pertussis toxins.";
RL   Int. J. Med. Microbiol. 290:301-305(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251;
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA   Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA   Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA   Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA   Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA   Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA   Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 248-326.
RC   STRAIN=BP165;
RX   PubMed=2873570; DOI=10.1073/pnas.83.13.4631;
RA   Nicosia A., Perugini M., Franzini C., Casagli M.C., Borri M.G., Antoni G.,
RA   Almoni M., Neri P., Ratti G., Rappuoli R.;
RT   "Cloning and sequencing of the pertussis toxin genes: operon structure and
RT   gene duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 83:4631-4635(1986).
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0065 (bug) family. {ECO:0000305}.
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DR   EMBL; AY234862; AAO61652.1; -; Genomic_DNA.
DR   EMBL; BX640422; CAE44037.1; -; Genomic_DNA.
DR   EMBL; M14378; AAA83979.1; -; Genomic_DNA.
DR   RefSeq; NP_882281.1; NC_002929.2.
DR   RefSeq; WP_010931647.1; NZ_CP039022.1.
DR   AlphaFoldDB; Q45389; -.
DR   SMR; Q45389; -.
DR   STRING; 257313.BP3782; -.
DR   GeneID; 45390928; -.
DR   KEGG; bpe:BP3782; -.
DR   PATRIC; fig|257313.5.peg.4086; -.
DR   eggNOG; COG3181; Bacteria.
DR   HOGENOM; CLU_045683_0_1_4; -.
DR   Proteomes; UP000002676; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.190.150; -; 1.
DR   InterPro; IPR005064; BUG.
DR   InterPro; IPR042100; Bug_dom1.
DR   PANTHER; PTHR42928; PTHR42928; 1.
DR   Pfam; PF03401; TctC; 1.
DR   PIRSF; PIRSF017082; YflP; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..326
FT                   /note="Protein BugT"
FT                   /id="PRO_0000036199"
SQ   SEQUENCE   326 AA;  33997 MW;  F1EDBEB9BEDE8290 CRC64;
     MNMTRLLAVI GIFIATAGIA APVSADTYPA RPIQMIVPFP PGGSTDVMAR VLARTLQDSL
     GQPVVVQNRA GAGGVIGTDA TAKSAADGYT LLLSSSSAPL AVGLSLMPSI PYKVLEDLVP
     VSMVGDVPLV LVTNPKLKLD SLDALIAQCK ARPGEVAFAL NALGSQAHLL TELFQLRTGA
     AINMIPYKGS GPAVVDLLGG VVAADIENMP AVLEHIRSGN LRALAILSSD RSTHFPAVPT
     MAELGYPEFV ASPWFAVMAP KGTDPKIIVL LNRHINEALQ SKAVVEAFAA QGATPVIATP
     DQTRGFIADE IQRWAGVVRE TGAKLK