ID   BUK1_THEMA              Reviewed;         357 AA.
AC   Q9X276;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Probable butyrate kinase 1 {ECO:0000255|HAMAP-Rule:MF_00542};
DE            Short=BK 1 {ECO:0000255|HAMAP-Rule:MF_00542};
DE            EC=2.7.2.7 {ECO:0000255|HAMAP-Rule:MF_00542};
DE   AltName: Full=Branched-chain carboxylic acid kinase 1 {ECO:0000255|HAMAP-Rule:MF_00542};
GN   Name=buk1 {ECO:0000255|HAMAP-Rule:MF_00542}; OrderedLocusNames=TM_1754;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + butanoate = ADP + butanoyl phosphate;
CC         Xref=Rhea:RHEA:13585, ChEBI:CHEBI:17968, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:58079, ChEBI:CHEBI:456216; EC=2.7.2.7;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00542};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00542}.
CC   -!- SIMILARITY: Belongs to the acetokinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00542}.
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DR   EMBL; AE000512; AAD36819.1; -; Genomic_DNA.
DR   PIR; C72214; C72214.
DR   RefSeq; NP_229552.1; NC_000853.1.
DR   RefSeq; WP_004082288.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9X276; -.
DR   SMR; Q9X276; -.
DR   STRING; 243274.THEMA_05465; -.
DR   EnsemblBacteria; AAD36819; AAD36819; TM_1754.
DR   KEGG; tma:TM1754; -.
DR   eggNOG; COG3426; Bacteria.
DR   InParanoid; Q9X276; -.
DR   OMA; ANDEGPF; -.
DR   OrthoDB; 537106at2; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047761; F:butyrate kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006083; P:acetate metabolic process; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00542; Butyrate_kinase; 1.
DR   InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR   InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR011245; Butyrate_kin.
DR   PANTHER; PTHR21060; PTHR21060; 1.
DR   PANTHER; PTHR21060:SF3; PTHR21060:SF3; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF036458; Butyrate_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02707; butyr_kinase; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome;
KW   Transferase.
FT   CHAIN           1..357
FT                   /note="Probable butyrate kinase 1"
FT                   /id="PRO_0000107674"
SQ   SEQUENCE   357 AA;  39283 MW;  826F1AC844DAEAEE CRC64;
     MYRILVINPG SSSTKVAVFE DEKKIAEKNV SHSVEELKKF KRSMDQEPLR RKAVEDFIDE
     VGYRIEDFSA IAARGGVLEP VPGGTYVVNE YMVDYLINRS PVDHVSNLAA VIGYKLGKPH
     GIPCFVVDPV SVDEMCDEAR FSGIPEIERK SYSHALNIKA VLRKVSREMG KTPEEVKIVV
     AHLGSGISVC ACKNGKIIDV NNANDEGPFS IERTGELPVG DVVKTAYSSK HSAAELKEEF
     TRKGGLLAYL GTKNLKKALD SMETSRKAKL VVEAMAYQIA KEIGGMCAVL GEKPDAIVIT
     GGMAHEIRFV RMITDYIEKF GKVEVIPGEL EMEALALGVL RVLRGEEKAM DYRSVVE