ID   BUK2_CALS4              Reviewed;         354 AA.
AC   Q8R828;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Probable butyrate kinase 2 {ECO:0000255|HAMAP-Rule:MF_00542};
DE            Short=BK 2 {ECO:0000255|HAMAP-Rule:MF_00542};
DE            EC=2.7.2.7 {ECO:0000255|HAMAP-Rule:MF_00542};
DE   AltName: Full=Branched-chain carboxylic acid kinase 2 {ECO:0000255|HAMAP-Rule:MF_00542};
GN   Name=buk2 {ECO:0000255|HAMAP-Rule:MF_00542}; OrderedLocusNames=TTE2205;
OS   Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM
OS   11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Caldanaerobacter.
OX   NCBI_TaxID=273068;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15242 / JCM 11007 / NBRC 100824 / MB4;
RX   PubMed=11997336; DOI=10.1101/gr.219302;
RA   Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y.,
RA   Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R.,
RA   Wang J., Yu J., Yang H.;
RT   "A complete sequence of the T. tengcongensis genome.";
RL   Genome Res. 12:689-700(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + butanoate = ADP + butanoyl phosphate;
CC         Xref=Rhea:RHEA:13585, ChEBI:CHEBI:17968, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:58079, ChEBI:CHEBI:456216; EC=2.7.2.7;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00542};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00542}.
CC   -!- SIMILARITY: Belongs to the acetokinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00542}.
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DR   EMBL; AE008691; AAM25360.1; -; Genomic_DNA.
DR   RefSeq; WP_009610633.1; NC_003869.1.
DR   AlphaFoldDB; Q8R828; -.
DR   SMR; Q8R828; -.
DR   STRING; 273068.TTE2205; -.
DR   PRIDE; Q8R828; -.
DR   EnsemblBacteria; AAM25360; AAM25360; TTE2205.
DR   KEGG; tte:TTE2205; -.
DR   eggNOG; COG3426; Bacteria.
DR   HOGENOM; CLU_048716_0_0_9; -.
DR   OrthoDB; 537106at2; -.
DR   Proteomes; UP000000555; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047761; F:butyrate kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00542; Butyrate_kinase; 1.
DR   InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR   InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR011245; Butyrate_kin.
DR   PANTHER; PTHR21060; PTHR21060; 1.
DR   PANTHER; PTHR21060:SF3; PTHR21060:SF3; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF036458; Butyrate_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02707; butyr_kinase; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome;
KW   Transferase.
FT   CHAIN           1..354
FT                   /note="Probable butyrate kinase 2"
FT                   /id="PRO_0000107677"
SQ   SEQUENCE   354 AA;  38552 MW;  BE6ED4C257D0835B CRC64;
     MFKVLVINPG STSTKVALYE DEKEIVRSDI THDVETLKNY KSVIEQLDLR LEAINKWLSE
     NGIKVLELSA IVVRGGLIKP VQSGTYVVND IMLEDLRKGV GGEHPSNLGG IIGRALADPY
     GIPVYTLDPV AVDEMEDVAR ISGLPELPRK SQSHALNIKA CIHRYARENN LKEEELNMIV
     AHMGGGISVA AIKGGRIVDV NNANQMGPFS PERTGSLPSM KVVEMCYSGK YTLEEMKKKI
     VGMGGLVAHL GTNDAREVVK RIEAGDKKAK LVFEAMAYQI AKEIGRMAAV LKGDVKTIIL
     TGGLAYSKPL IEIIIDMVGF IAPITLYPGG DEMEALRDGA LRVLRGQETP KIYG