ID   TRIQK_DANRE             Reviewed;          84 AA.
AC   A5WVU9; B2B9E2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Triple QxxK/R motif-containing protein;
DE   AltName: Full=Triple repetitive-sequence of QXXK/R protein homolog;
GN   Name=triqk; ORFNames=si:ch211-160k22.1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC   TISSUE=Egg;
RX   PubMed=18828657; DOI=10.2108/zsj.25.706;
RA   Onuma Y., Watanabe A., Aburatani H., Asashima M., Whitman M.;
RT   "TRIQK, a novel family of small proteins localized to the endoplasmic
RT   reticulum membrane, is conserved across vertebrates.";
RL   Zool. Sci. 25:706-713(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
CC   -!- FUNCTION: May play a role in cell growth and maintenance of cell
CC       morphology. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed from the oblong to the hatching stage.
CC       {ECO:0000269|PubMed:18828657}.
CC   -!- SIMILARITY: Belongs to the TRIQK family. {ECO:0000305}.
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DR   EMBL; DQ351293; ABC84192.1; -; mRNA.
DR   EMBL; CT027830; CAN88662.1; -; Genomic_DNA.
DR   RefSeq; NP_001120728.2; NM_001127256.3.
DR   AlphaFoldDB; A5WVU9; -.
DR   SMR; A5WVU9; -.
DR   STRING; 7955.ENSDARP00000122282; -.
DR   PaxDb; A5WVU9; -.
DR   Ensembl; ENSDART00000142275; ENSDARP00000122282; ENSDARG00000076296.
DR   Ensembl; ENSDART00000181800; ENSDARP00000152272; ENSDARG00000076296.
DR   GeneID; 100147776; -.
DR   KEGG; dre:100147776; -.
DR   CTD; 286144; -.
DR   ZFIN; ZDB-GENE-070705-75; triqk.
DR   eggNOG; ENOG502S3QR; Eukaryota.
DR   GeneTree; ENSGT00390000017350; -.
DR   HOGENOM; CLU_191636_0_0_1; -.
DR   InParanoid; A5WVU9; -.
DR   OMA; NIGKQDY; -.
DR   OrthoDB; 1639030at2759; -.
DR   PhylomeDB; A5WVU9; -.
DR   TreeFam; TF328583; -.
DR   PRO; PR:A5WVU9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 19.
DR   Bgee; ENSDARG00000076296; Expressed in early embryo and 25 other tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR024842; TRIQK.
DR   PANTHER; PTHR20583; PTHR20583; 1.
DR   Pfam; PF15168; TRIQK; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..84
FT                   /note="Triple QxxK/R motif-containing protein"
FT                   /id="PRO_0000340677"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        84
FT                   /note="D -> N (in Ref. 1; ABC84192)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   84 AA;  9500 MW;  DB4DBD78EEEC554F CRC64;
     MGKKDASSVK LPVDQYRKQI GKQDYKKTKP VLRATRLKAE AKRSAPGIRD IILVIVAVLL
     FLLGVYAFFY LNLSTELDLD VDMD