ID   TRIQK_MOUSE             Reviewed;          86 AA.
AC   B2B9E1;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Triple QxxK/R motif-containing protein;
DE   AltName: Full=Triple repetitive-sequence of QXXK/R protein homolog;
GN   Name=Triqk; Synonyms=Gm11818;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, AND TISSUE SPECIFICITY.
RX   PubMed=18828657; DOI=10.2108/zsj.25.706;
RA   Onuma Y., Watanabe A., Aburatani H., Asashima M., Whitman M.;
RT   "TRIQK, a novel family of small proteins localized to the endoplasmic
RT   reticulum membrane, is conserved across vertebrates.";
RL   Zool. Sci. 25:706-713(2008).
CC   -!- FUNCTION: May play a role in cell growth and maintenance of cell
CC       morphology. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in heart, brain, spleen, lung, liver,
CC       skeletal muscle, kidney and testis. {ECO:0000269|PubMed:18828657}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in embryo from 7 to 17 dpc.
CC       {ECO:0000269|PubMed:18828657}.
CC   -!- SIMILARITY: Belongs to the TRIQK family. {ECO:0000305}.
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DR   EMBL; DQ351292; ABC84191.1; -; mRNA.
DR   CCDS; CCDS71348.1; -.
DR   RefSeq; NP_001165272.1; NM_001171801.1.
DR   RefSeq; NP_776107.2; NM_173746.3.
DR   AlphaFoldDB; B2B9E1; -.
DR   SMR; B2B9E1; -.
DR   STRING; 10090.ENSMUSP00000139205; -.
DR   PhosphoSitePlus; B2B9E1; -.
DR   MaxQB; B2B9E1; -.
DR   PRIDE; B2B9E1; -.
DR   ProteomicsDB; 259184; -.
DR   Antibodypedia; 77803; 2 antibodies from 2 providers.
DR   DNASU; 208820; -.
DR   Ensembl; ENSMUST00000143186; ENSMUSP00000139205; ENSMUSG00000055963.
DR   Ensembl; ENSMUST00000183345; ENSMUSP00000138966; ENSMUSG00000055963.
DR   GeneID; 208820; -.
DR   KEGG; mmu:208820; -.
DR   UCSC; uc008sas.2; mouse.
DR   CTD; 286144; -.
DR   MGI; MGI:3650048; Triqk.
DR   VEuPathDB; HostDB:ENSMUSG00000055963; -.
DR   eggNOG; ENOG502S3QR; Eukaryota.
DR   GeneTree; ENSGT00390000017350; -.
DR   HOGENOM; CLU_191636_0_0_1; -.
DR   InParanoid; B2B9E1; -.
DR   OMA; NIGKQDY; -.
DR   OrthoDB; 1639030at2759; -.
DR   PhylomeDB; B2B9E1; -.
DR   BioGRID-ORCS; 208820; 4 hits in 68 CRISPR screens.
DR   ChiTaRS; Triqk; mouse.
DR   PRO; PR:B2B9E1; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; B2B9E1; protein.
DR   Bgee; ENSMUSG00000055963; Expressed in otolith organ and 197 other tissues.
DR   Genevisible; B2B9E1; MM.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR024842; TRIQK.
DR   PANTHER; PTHR20583; PTHR20583; 1.
DR   Pfam; PF15168; TRIQK; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..86
FT                   /note="Triple QxxK/R motif-containing protein"
FT                   /id="PRO_0000398147"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   86 AA;  9722 MW;  A00DA911D51C1AE2 CRC64;
     MGRKDSSNTK LPVDQYRKQI GKQDYKKTKP ILRATKLKAE AKKTAIGIKE VGLMLAAILA
     LLLAFYAFFY LRLSTNIDSD LDLDED