TRL12_ARATH
ID TRL12_ARATH Reviewed; 245 AA.
AC Q9XFI1; Q2HIW4;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=Thioredoxin-like 1-2, chloroplastic;
DE AltName: Full=Atypical cysteine/histidine-rich thioredoxin 5;
DE Short=AtACHT5;
DE AltName: Full=Lilium-type thioredoxin 1-2;
DE Flags: Precursor;
GN OrderedLocusNames=At5g61440; ORFNames=MFB13.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10498962; DOI=10.1016/s1360-1385(99)01475-2;
RA Meyer Y., Verdoucq L., Vignols F.;
RT "Plant thioredoxins and glutaredoxins: identity and putative roles.";
RL Trends Plant Sci. 4:388-394(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825616; DOI=10.1093/mp/ssn076;
RA Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.;
RT "Comparative genomic study of the thioredoxin family in photosynthetic
RT organisms with emphasis on Populus trichocarpa.";
RL Mol. Plant 2:308-322(2009).
RN [7]
RP SUBCELLULAR LOCATION.
RX PubMed=19109414; DOI=10.1104/pp.108.128314;
RA Dangoor I., Peled-Zehavi H., Levitan A., Pasand O., Danon A.;
RT "A small family of chloroplast atypical thioredoxins.";
RL Plant Physiol. 149:1240-1250(2009).
CC -!- FUNCTION: Probable thiol-disulfide oxidoreductase that may participate
CC in various redox reactions.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:19109414}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
CC -!- CAUTION: The active site contains a CGGC motif wich differs from the
CC conserved CGPC motif. {ECO:0000305}.
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DR EMBL; AF144389; AAD35007.1; -; mRNA.
DR EMBL; AB010073; BAB08500.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97469.1; -; Genomic_DNA.
DR EMBL; BT024467; ABD19648.1; -; mRNA.
DR EMBL; AK229043; BAF00926.1; -; mRNA.
DR RefSeq; NP_200952.1; NM_125537.3.
DR AlphaFoldDB; Q9XFI1; -.
DR SMR; Q9XFI1; -.
DR STRING; 3702.AT5G61440.1; -.
DR PaxDb; Q9XFI1; -.
DR PRIDE; Q9XFI1; -.
DR ProteomicsDB; 245233; -.
DR EnsemblPlants; AT5G61440.1; AT5G61440.1; AT5G61440.
DR GeneID; 836265; -.
DR Gramene; AT5G61440.1; AT5G61440.1; AT5G61440.
DR KEGG; ath:AT5G61440; -.
DR Araport; AT5G61440; -.
DR TAIR; locus:2163168; AT5G61440.
DR eggNOG; KOG0907; Eukaryota.
DR HOGENOM; CLU_055041_0_0_1; -.
DR InParanoid; Q9XFI1; -.
DR OMA; MHQASNI; -.
DR OrthoDB; 1482186at2759; -.
DR PhylomeDB; Q9XFI1; -.
DR PRO; PR:Q9XFI1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9XFI1; baseline and differential.
DR Genevisible; Q9XFI1; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0045454; P:cell redox homeostasis; IBA:GO_Central.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Disulfide bond; Electron transport; Plastid;
KW Redox-active center; Reference proteome; Transit peptide; Transport.
FT TRANSIT 1..92
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 93..245
FT /note="Thioredoxin-like 1-2, chloroplastic"
FT /id="PRO_0000034168"
FT DOMAIN 93..194
FT /note="Thioredoxin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT ACT_SITE 117
FT /note="Nucleophile"
FT /evidence="ECO:0000255"
FT ACT_SITE 120
FT /note="Nucleophile"
FT /evidence="ECO:0000255"
FT DISULFID 117..120
FT /note="Redox-active"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ SEQUENCE 245 AA; 26890 MW; 88F23798E5124CF7 CRC64;
MDAISSLGTN CVLSGVSPFS QENQSKSKLS PFMSLDLKEH PMASADFTNQ TLTAFSSSSA
SPFQAKTSSI GMSRGMRWWE KSTNHNMLEI QSANHLVDSL LNAGDRLVVL DFYSPGCGGC
KSLHPKICQL AETNPNVMFL KVNQEELRTM CHGLNVHVLP FFKFYRGAEG KVCSFSCTIA
TINKFKKALD KHGSERCSLG DAKGLDEKEL AALASVGELK MNSLTMHQAS NIGYKTEEQY
QTMVL
