BUK_GEOSE
ID BUK_GEOSE Reviewed; 46 AA.
AC P54621;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Probable butyrate kinase;
DE Short=BK;
DE EC=2.7.2.7;
DE AltName: Full=Branched-chain carboxylic acid kinase;
DE Flags: Fragment;
GN Name=buk;
OS Geobacillus stearothermophilus (Bacillus stearothermophilus).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX NCBI_TaxID=1422;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 12980 / DSM 22 / CCM 2062 / JCM 2501 / NBRC 12550 / NCIMB 8923
RC / NCTC 10339 / R-35646 / VKM B-510;
RX PubMed=3069133; DOI=10.1021/bi00425a026;
RA Nagata S., Tanizawa K., Esaki N., Sakamoto Y., Ohshima T., Tanaka H.,
RA Soda K.;
RT "Gene cloning and sequence determination of leucine dehydrogenase from
RT Bacillus stearothermophilus and structural comparison with other NAD(P)+-
RT dependent dehydrogenases.";
RL Biochemistry 27:9056-9062(1988).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + butanoate = ADP + butanoyl phosphate;
CC Xref=Rhea:RHEA:13585, ChEBI:CHEBI:17968, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:58079, ChEBI:CHEBI:456216; EC=2.7.2.7;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the acetokinase family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA22570.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; M22977; AAA22570.1; ALT_FRAME; Genomic_DNA.
DR AlphaFoldDB; P54621; -.
DR SMR; P54621; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0047761; F:butyrate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR SUPFAM; SSF53067; SSF53067; 1.
DR PROSITE; PS01075; ACETATE_KINASE_1; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Transferase.
FT CHAIN 1..>46
FT /note="Probable butyrate kinase"
FT /id="PRO_0000107665"
FT NON_TER 46
SQ SEQUENCE 46 AA; 5334 MW; 45035BC58FAC6832 CRC64;
MQEQKFRILT INPGSTSTKI GVFENERAIV EKTIRHEGRC FGNIKR