ID   TRM2_EHV1B              Reviewed;         162 AA.
AC   P28953; Q6DLI4;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   23-FEB-2022, entry version 72.
DE   RecName: Full=Tripartite terminase subunit 2 {ECO:0000255|HAMAP-Rule:MF_04015};
GN   Name=TRM2 {ECO:0000255|HAMAP-Rule:MF_04015}; OrderedLocusNames=27;
OS   Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=31520;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA   Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus-1.";
RL   Virology 189:304-316(1992).
CC   -!- FUNCTION: Component of the molecular motor that translocates viral
CC       genomic DNA in empty capsid during DNA packaging. Forms a tripartite
CC       terminase complex together with TRM1 and TRM3 in the host cytoplasm.
CC       Once the complex reaches the host nucleus, it interacts with the capsid
CC       portal vertex. This portal forms a ring in which genomic DNA is
CC       translocated into the capsid. {ECO:0000255|HAMAP-Rule:MF_04015}.
CC   -!- SUBUNIT: Associates with TRM1 and TRM3 to form the tripartite terminase
CC       complex. {ECO:0000255|HAMAP-Rule:MF_04015}.
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04015}.
CC       Note=Found associated with the external surface of the viral capsid
CC       during assembly and DNA packaging, but seems absent in extracellular
CC       mature virions. {ECO:0000255|HAMAP-Rule:MF_04015}.
CC   -!- SIMILARITY: Belongs to the herpesviridae TRM2 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04015}.
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DR   EMBL; AY665713; AAT67284.1; -; Genomic_DNA.
DR   PIR; A36798; WZBEB9.
DR   SMR; P28953; -.
DR   Proteomes; UP000001189; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019073; P:viral DNA genome packaging; IEA:UniProtKB-UniRule.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04015; HSV_TRM2; 1.
DR   InterPro; IPR005208; Herpes_TT2.
DR   Pfam; PF03581; Herpes_UL33; 1.
PE   3: Inferred from homology;
KW   Host nucleus; Reference proteome; Viral genome packaging;
KW   Viral release from host cell.
FT   CHAIN           1..162
FT                   /note="Tripartite terminase subunit 2"
FT                   /id="PRO_0000116024"
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   162 AA;  17994 MW;  54ACA1E42E4DE1D0 CRC64;
     MYGRSNAPGC QPPVRAHPPS SPMTSRLQLA AMEQNASDAA LSGMQQARSR QASPKRLRDL
     IPSSDVESMS LNALDDAYGH HDFSVWFEDL MPPEMELLMP TTDAKLNYLS FTRRLASSVF
     HSPDNRMPGG ACDHTSALDA RKERFATIIN KFLDLHQILH DA