BUK_PHOV8
ID BUK_PHOV8 Reviewed; 354 AA.
AC A6KZZ5;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Probable butyrate kinase {ECO:0000255|HAMAP-Rule:MF_00542};
DE Short=BK {ECO:0000255|HAMAP-Rule:MF_00542};
DE EC=2.7.2.7 {ECO:0000255|HAMAP-Rule:MF_00542};
DE AltName: Full=Branched-chain carboxylic acid kinase {ECO:0000255|HAMAP-Rule:MF_00542};
GN Name=buk {ECO:0000255|HAMAP-Rule:MF_00542}; OrderedLocusNames=BVU_1320;
OS Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 /
OS NBRC 14291 / NCTC 11154) (Bacteroides vulgatus).
OC Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Phocaeicola.
OX NCBI_TaxID=435590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC
RC 11154;
RX PubMed=17579514; DOI=10.1371/journal.pbio.0050156;
RA Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C.,
RA Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H.,
RA Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K.,
RA Knight R.D., Gordon J.I.;
RT "Evolution of symbiotic bacteria in the distal human intestine.";
RL PLoS Biol. 5:1574-1586(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + butanoate = ADP + butanoyl phosphate;
CC Xref=Rhea:RHEA:13585, ChEBI:CHEBI:17968, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:58079, ChEBI:CHEBI:456216; EC=2.7.2.7;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00542};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00542}.
CC -!- SIMILARITY: Belongs to the acetokinase family. {ECO:0000255|HAMAP-
CC Rule:MF_00542}.
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DR EMBL; CP000139; ABR39009.1; -; Genomic_DNA.
DR RefSeq; WP_005838784.1; NC_009614.1.
DR AlphaFoldDB; A6KZZ5; -.
DR SMR; A6KZZ5; -.
DR STRING; 435590.BVU_1320; -.
DR EnsemblBacteria; ABR39009; ABR39009; BVU_1320.
DR GeneID; 66747870; -.
DR KEGG; bvu:BVU_1320; -.
DR eggNOG; COG3426; Bacteria.
DR HOGENOM; CLU_048716_0_0_10; -.
DR OMA; IWHALNQ; -.
DR OrthoDB; 537106at2; -.
DR BioCyc; BVUL435590:G1G59-1378-MON; -.
DR Proteomes; UP000002861; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0047761; F:butyrate kinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00542; Butyrate_kinase; 1.
DR InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR011245; Butyrate_kin.
DR PANTHER; PTHR21060; PTHR21060; 1.
DR PANTHER; PTHR21060:SF3; PTHR21060:SF3; 1.
DR Pfam; PF00871; Acetate_kinase; 1.
DR PIRSF; PIRSF036458; Butyrate_kin; 1.
DR PRINTS; PR00471; ACETATEKNASE.
DR SUPFAM; SSF53067; SSF53067; 2.
DR TIGRFAMs; TIGR02707; butyr_kinase; 1.
DR PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome;
KW Transferase.
FT CHAIN 1..354
FT /note="Probable butyrate kinase"
FT /id="PRO_1000061066"
SQ SEQUENCE 354 AA; 38266 MW; FC92C470D1BB4F77 CRC64;
MKIFVINPGS TSTKIALFID EKPVWAAGAH HTADDLSEFH HVNEQYAYRK DFVLRLLAEA
DIPLDFDAVI ARGGLLKPTP GGVYAINEQM KHDLLNARME HACNLGALIA DEIARECHCP
AYIADPEVVD ELQPAARLTG IPEIERISIF HALNSKAVSR KYAASIGKHY EELNLIVVHL
GGGISVGAHC KGRVIDVNNA LNGEGPFSPE RAGTIPADQL AELCFSGKYT LKQIKKMLNG
KGGLTAHLGM NDVVTIARKA SEGEEPYKGV LDAMLYTVAK QAGAMYVTLR GQVDAIILTG
GIAHSDYCVG ILKEQIDYLA PVVLMPGEDE MGSLAYNALG ALKGELPLQV YRPE
