ID   BUTH_ANDAU              Reviewed;          34 AA.
AC   P56685; P81617;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Buthinin;
OS   Androctonus australis (Sahara scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Androctonus.
OX   NCBI_TaxID=6858;
RN   [1]
RP   PROTEIN SEQUENCE, CHARACTERIZATION, AND MASS SPECTROMETRY.
RC   STRAIN=Hector; TISSUE=Hemolymph;
RX   PubMed=8939880; DOI=10.1074/jbc.271.47.29537;
RA   Ehret-Sabatier L., Loew D., Goyffon M., Fehlbaum P., Hoffmann J.A.,
RA   van Dorsselaer A., Bulet P.;
RT   "Characterization of novel cysteine-rich antimicrobial peptides from
RT   scorpion blood.";
RL   J. Biol. Chem. 271:29537-29544(1996).
CC   -!- FUNCTION: Active against both Gram-positive and Gram-negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- PTM: Contains three disulfide bonds.
CC   -!- MASS SPECTROMETRY: Mass=3968.5; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:8939880};
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DR   AlphaFoldDB; P56685; -.
DR   SMR; P56685; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW   Secreted.
FT   PEPTIDE         1..34
FT                   /note="Buthinin"
FT                   /id="PRO_0000044689"
SQ   SEQUENCE   34 AA;  3975 MW;  03323E99B7388B07 CRC64;
     SIVPIRCRSN RDCRRFCGFR GGRCTYARQC LCGY