ID   BYE1_CANGA              Reviewed;         607 AA.
AC   Q6FJ00;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Transcription factor BYE1;
GN   Name=BYE1; OrderedLocusNames=CAGL0M10285g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Negative regulator of transcription elongation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00651}.
CC   -!- SIMILARITY: Belongs to the BYE1 family. {ECO:0000305}.
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DR   EMBL; CR380959; CAG62772.1; -; Genomic_DNA.
DR   RefSeq; XP_449794.1; XM_449794.1.
DR   AlphaFoldDB; Q6FJ00; -.
DR   SMR; Q6FJ00; -.
DR   STRING; 5478.XP_449794.1; -.
DR   EnsemblFungi; CAG62772; CAG62772; CAGL0M10285g.
DR   GeneID; 2891358; -.
DR   KEGG; cgr:CAGL0M10285g; -.
DR   CGD; CAL0136525; CAGL0M10285g.
DR   VEuPathDB; FungiDB:CAGL0M10285g; -.
DR   eggNOG; KOG1634; Eukaryota.
DR   HOGENOM; CLU_495285_0_0_1; -.
DR   InParanoid; Q6FJ00; -.
DR   OMA; RTHKGDI; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.472.30; -; 1.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR003618; TFIIS_cen_dom.
DR   InterPro; IPR036575; TFIIS_cen_dom_sf.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF07500; TFIIS_M; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00510; TFS2M; 1.
DR   SUPFAM; SSF46942; SSF46942; 1.
DR   SUPFAM; SSF57903; SSF57903; 1.
DR   PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..607
FT                   /note="Transcription factor BYE1"
FT                   /id="PRO_0000324848"
FT   DOMAIN          239..374
FT                   /note="TFIIS central"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00651"
FT   ZN_FING         44..122
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"
FT   REGION          180..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          369..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..440
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   607 AA;  70176 MW;  A621AD6B3946BC8A CRC64;
     MESLRKSSRS TKGKNTYLEV LRRQEEEEYE QRVNRPKKEK VQEIVHCSPC GTTDANYVED
     EDPYGEMIQC DQCDTWQHIN CMLQVKDIKV PKELENSDDV DSLSKLLVNS EDKYYCDRCI
     YKSQLREERR AYKELNKSEM IGDNDILDEP KEHPDEYVDD QDEDQDFILS KDTANIAEVD
     DDEFVENDDN RVKKDKRKRK PSNSAITTTK TVPKKKARVI TDDQTETETI PSEDSYAKVR
     TNARKMLVTL FKNYIIPDTL KNNVFEIVKG HDEQSISDEF AEEMESKLFS HCRSISNYKT
     LISVYTEKVR VLFSNLKDPK NLSLKEAVIN RQLDLEQLVS MSATDLANPD LQSMKKKIDS
     QKIDSLVIPN QPLDKLKQDN SEDDHNSFEF TNPTFTKTFN PKDIHESNSN NRPYTTDSPT
     NSYTDEPDSM KSDSNNGVDT NDQNILNVKF KLDYNEVDLN VVGTFKFLGS TLLDENQEHK
     IYQAVVGDGK LIYEGRLHTK IATEYISEIK TTRAVLAYQL LPSASHREKY EQLVEFMDDL
     DRVLGMKPRK PYVKNMYILS SLLGKLPDIL QILTTDESIA KKRIDLSRIN DNDKTLYLVV
     VVKPEIV