BYR3_SCHPO
ID BYR3_SCHPO Reviewed; 179 AA.
AC P36627;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Cellular nucleic acid-binding protein homolog;
GN Name=byr3; ORFNames=SPAC13D6.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SP870;
RX PubMed=1515675; DOI=10.1091/mbc.3.7.721;
RA Xu H.-P., Rajavashisth T., Grewal N., Jung V., Riggs M., Rodgers L.,
RA Wigler M.;
RT "A gene encoding a protein with seven zinc finger domains acts on the
RT sexual differentiation pathways of Schizosaccharomyces pombe.";
RL Mol. Biol. Cell 3:721-734(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Acts in the sexual differentiation pathway. Is required for
CC efficient conjugation. Double-stranded DNA-binding protein.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- PTM: Phosphorylated.
CC -!- SIMILARITY: To human CNBP and to retroviral nucleic acid binding
CC proteins (NBP). {ECO:0000305}.
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DR EMBL; S45038; AAB23116.1; -; Genomic_DNA.
DR EMBL; CU329670; CAA93542.1; -; Genomic_DNA.
DR PIR; T37622; T37622.
DR RefSeq; NP_593680.1; NM_001019112.2.
DR AlphaFoldDB; P36627; -.
DR BioGRID; 279276; 33.
DR STRING; 4896.SPAC13D6.02c.1; -.
DR iPTMnet; P36627; -.
DR MaxQB; P36627; -.
DR PaxDb; P36627; -.
DR PRIDE; P36627; -.
DR EnsemblFungi; SPAC13D6.02c.1; SPAC13D6.02c.1:pep; SPAC13D6.02c.
DR GeneID; 2542829; -.
DR KEGG; spo:SPAC13D6.02c; -.
DR PomBase; SPAC13D6.02c; byr3.
DR VEuPathDB; FungiDB:SPAC13D6.02c; -.
DR eggNOG; KOG4400; Eukaryota.
DR HOGENOM; CLU_058879_2_0_1; -.
DR InParanoid; P36627; -.
DR OMA; SHQARDC; -.
DR PhylomeDB; P36627; -.
DR PRO; PR:P36627; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; ISO:PomBase.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0008494; F:translation activator activity; ISO:PomBase.
DR GO; GO:0045182; F:translation regulator activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:2000767; P:positive regulation of cytoplasmic translation; ISO:PomBase.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR Pfam; PF00098; zf-CCHC; 7.
DR SMART; SM00343; ZnF_C2HC; 7.
DR SUPFAM; SSF57756; SSF57756; 4.
DR PROSITE; PS50158; ZF_CCHC; 7.
PE 4: Predicted;
KW DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN 1..179
FT /note="Cellular nucleic acid-binding protein homolog"
FT /id="PRO_0000065031"
FT ZN_FING 17..34
FT /note="CCHC-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 36..53
FT /note="CCHC-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 58..75
FT /note="CCHC-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 83..100
FT /note="CCHC-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 116..133
FT /note="CCHC-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 135..152
FT /note="CCHC-type 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT ZN_FING 157..174
FT /note="CCHC-type 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
SQ SEQUENCE 179 AA; 19343 MW; 749B93904E645D60 CRC64;
MESESVPTVP QTTRPGPRCY NCGENGHQAR ECTKGSICYN CNQTGHKASE CTEPQQEKTC
YACGTAGHLV RDCPSSPNPR QGAECYKCGR VGHIARDCRT NGQQSGGRFG GHRSNMNCYA
CGSYGHQARD CTMGVKCYSC GKIGHRSFEC QQASDGQLCY KCNQPGHIAV NCTSPVIEA
