ID   BYST_MONBE              Reviewed;         414 AA.
AC   A9UNU6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Bystin;
GN   Name=bysl; ORFNames=17006;
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154;
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- FUNCTION: Required for processing of 20S pre-rRNA precursor and
CC       biogenesis of 40S ribosomal subunits. {ECO:0000250|UniProtKB:Q13895}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q13895}.
CC   -!- SIMILARITY: Belongs to the bystin family. {ECO:0000305}.
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DR   EMBL; CH991543; EDQ92305.1; -; Genomic_DNA.
DR   RefSeq; XP_001742067.1; XM_001742015.1.
DR   AlphaFoldDB; A9UNU6; -.
DR   SMR; A9UNU6; -.
DR   STRING; 81824.XP_001742067.1; -.
DR   EnsemblProtists; EDQ92305; EDQ92305; MONBRDRAFT_17006.
DR   GeneID; 5887806; -.
DR   KEGG; mbr:MONBRDRAFT_17006; -.
DR   eggNOG; KOG3871; Eukaryota.
DR   InParanoid; A9UNU6; -.
DR   OMA; AGGQEKH; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   InterPro; IPR007955; Bystin.
DR   PANTHER; PTHR12821; PTHR12821; 1.
DR   Pfam; PF05291; Bystin; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..414
FT                   /note="Bystin"
FT                   /id="PRO_0000327727"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   414 AA;  47686 MW;  4EB485414BA6336D CRC64;
     MSAKRNTKLR HAPLEHAYVD DKSVRRNKRS KQRGRMQDDE SVDAPLNEKQ AQVIARQAQL
     QQNEEDVSDS EQTGQPVDID VPSDDEGQAD DLAQPEDAYR HFEIDEHDEV ALRAFMPAEP
     AQRRTLADII MEKIQGKRTE VASQVSQTGP RELNPKVIEV YQGVGQVLSR YRSGKLPKAF
     KIIPRLKNWE EIVYITEPEN WTAASMYAAT RLFASNLKEK MAQRFYNLIL LPRVRDDIAE
     YKRLNFHLYQ AIKKAIFKPG AFFKGFLLPL CEAGDCTLRE AVIIGGILVR KSIPVLHSSA
     AMLKMAEMPY SGATSIFLRV LLDKKYSLPF RVVDAVVAHF YRFNADHRQL PVLWHQCLLV
     FVQRYKEDIT SEQKRALLDV LRSHNHYAIT PEIRRELVQS KSRDREMPLE ESSR