ID   BYST_NEMVE              Reviewed;         430 AA.
AC   A7S7F2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Bystin;
GN   Name=bysl; ORFNames=v1g167370;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Required for processing of 20S pre-rRNA precursor and
CC       biogenesis of 40S ribosomal subunits. {ECO:0000250|UniProtKB:Q13895}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q13895}.
CC   -!- SIMILARITY: Belongs to the bystin family. {ECO:0000305}.
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DR   EMBL; DS469592; EDO40390.1; -; Genomic_DNA.
DR   RefSeq; XP_001632453.1; XM_001632403.1.
DR   AlphaFoldDB; A7S7F2; -.
DR   SMR; A7S7F2; -.
DR   STRING; 45351.EDO40390; -.
DR   EnsemblMetazoa; EDO40390; EDO40390; NEMVEDRAFT_v1g167370.
DR   GeneID; 5512119; -.
DR   KEGG; nve:5512119; -.
DR   eggNOG; KOG3871; Eukaryota.
DR   HOGENOM; CLU_029727_0_1_1; -.
DR   InParanoid; A7S7F2; -.
DR   OMA; AGGQEKH; -.
DR   OrthoDB; 1193442at2759; -.
DR   PhylomeDB; A7S7F2; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   InterPro; IPR007955; Bystin.
DR   PANTHER; PTHR12821; PTHR12821; 1.
DR   Pfam; PF05291; Bystin; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..430
FT                   /note="Bystin"
FT                   /id="PRO_0000327728"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          65..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..106
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  49803 MW;  C5771CDE22DA7EA9 CRC64;
     MGKDKKDRKH KGGLTEDILE KNVTKPSKRV KHRRERQADS VESFVEEKLS KKILEQARQQ
     QDELMEEYGF RKTGDRKTLK SAQTTLGTPD LDRIDDDDED DSDDGASMTS ETYYENVEVD
     EEEEKAFEMF MSQEAPTRRT LADVIMEKIQ DKKTEIESHM SEQSTAPQMD ERLVKVFKGV
     GEILKKYRSG KLPKAFKFIP SLTNWEEVLF ITEPDEWSAA ALFQATKIFV SNLNAKMAQR
     FFNLVLLPRI QDDIAEYKRL NYHLYMALKK ALFKPAAFFK GILLPMCESG NCSLREAIII
     SSVLAKTTIP VLHSSAVILK IAEMNYSGAN SIFLRTLFDK KYALPYRVID AAVYHFLRFL
     TDKRTLPVLW HQCLLTFVQR YKEDISSEQK EALMELCRVH VHDKITPEVR RELVHSKSRD
     METDQPMEST