TRNH5_ARATH
ID TRNH5_ARATH Reviewed; 322 AA.
AC Q9ZW12; Q84W78;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Tropinone reductase homolog At2g29260, chloroplastic {ECO:0000305};
DE EC=1.1.1.- {ECO:0000305};
DE Flags: Precursor;
GN OrderedLocusNames=At2g29260 {ECO:0000312|Araport:AT2G29260};
GN ORFNames=F16P2.36 {ECO:0000312|EMBL:AAC95209.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 11-322.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19027726; DOI=10.1016/j.cbi.2008.10.040;
RA Persson B., Kallberg Y., Bray J.E., Bruford E., Dellaporta S.L.,
RA Favia A.D., Duarte R.G., Joernvall H., Kavanagh K.L., Kedishvili N.,
RA Kisiela M., Maser E., Mindnich R., Orchard S., Penning T.M., Thornton J.M.,
RA Adamski J., Oppermann U.;
RT "The SDR (short-chain dehydrogenase/reductase and related enzymes)
RT nomenclature initiative.";
RL Chem. Biol. Interact. 178:94-98(2009).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. SDR65C subfamily. {ECO:0000305}.
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DR EMBL; AC004561; AAC95209.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08226.1; -; Genomic_DNA.
DR EMBL; BT004138; AAO42159.1; -; mRNA.
DR PIR; D84694; D84694.
DR RefSeq; NP_180489.1; NM_128482.4.
DR AlphaFoldDB; Q9ZW12; -.
DR SMR; Q9ZW12; -.
DR STRING; 3702.AT2G29260.1; -.
DR PaxDb; Q9ZW12; -.
DR PRIDE; Q9ZW12; -.
DR ProteomicsDB; 232407; -.
DR EnsemblPlants; AT2G29260.1; AT2G29260.1; AT2G29260.
DR GeneID; 817475; -.
DR Gramene; AT2G29260.1; AT2G29260.1; AT2G29260.
DR KEGG; ath:AT2G29260; -.
DR Araport; AT2G29260; -.
DR TAIR; locus:2043087; AT2G29260.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_1_1; -.
DR InParanoid; Q9ZW12; -.
DR OMA; TWGGPFD; -.
DR OrthoDB; 1194344at2759; -.
DR PhylomeDB; Q9ZW12; -.
DR BioCyc; ARA:AT2G29260-MON; -.
DR PRO; PR:Q9ZW12; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZW12; baseline and differential.
DR Genevisible; Q9ZW12; AT.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR InterPro; IPR045000; TR.
DR PANTHER; PTHR42898; PTHR42898; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; NADP; Oxidoreductase; Plastid; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..61
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 62..322
FT /note="Tropinone reductase homolog At2g29260,
FT chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000432360"
FT BINDING 74..98
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250|UniProtKB:P50162"
FT BINDING 207
FT /ligand="substrate"
FT /evidence="ECO:0000250|UniProtKB:P50162"
FT CONFLICT 151
FT /note="I -> T (in Ref. 3; AAO42159)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 322 AA; 35238 MW; 2AF32C812B327789 CRC64;
MVLDMASHLY TNPPQNLHFI SSSSSLKPHL CLSFKRINPK HKSSSSSVFV PYASQSSIAI
TSKERWSLNG MSALVTGGTR GIGRAIVEEL AGLGAEVHTC ARNEYELENC LSDWNRSGFR
VAGSVCDVSD RSQREALMET VSSVFEGKLH ILVNNVGTNI RKPMVEFTAG EFSTLMSTNF
ESVFHLCQLA YPLLRESKAG SVVFISSVSG FVSLKNMSVQ SSTKGAINQL TRSLACEWAK
DNIRINAVAP WYIKTSMVEQ VLSNKEYLEE VYSVTPLGRL GEPREVSSAV AFLCLPASSY
ITGQILCVDG GMSINGFFPR HD
