TRNHE_ARATH
ID TRNHE_ARATH Reviewed; 262 AA.
AC O49332;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Tropinone reductase homolog At2g30670 {ECO:0000305};
DE EC=1.1.1.- {ECO:0000305};
GN OrderedLocusNames=At2g30670 {ECO:0000312|Araport:AT2G30670};
GN ORFNames=T11J7.6 {ECO:0000312|EMBL:AAC02738.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19027726; DOI=10.1016/j.cbi.2008.10.040;
RA Persson B., Kallberg Y., Bray J.E., Bruford E., Dellaporta S.L.,
RA Favia A.D., Duarte R.G., Joernvall H., Kavanagh K.L., Kedishvili N.,
RA Kisiela M., Maser E., Mindnich R., Orchard S., Penning T.M., Thornton J.M.,
RA Adamski J., Oppermann U.;
RT "The SDR (short-chain dehydrogenase/reductase and related enzymes)
RT nomenclature initiative.";
RL Chem. Biol. Interact. 178:94-98(2009).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. SDR65C subfamily. {ECO:0000305}.
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DR EMBL; AC002340; AAC02738.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08425.1; -; Genomic_DNA.
DR PIR; C84711; C84711.
DR RefSeq; NP_180625.1; NM_128619.2.
DR AlphaFoldDB; O49332; -.
DR SMR; O49332; -.
DR STRING; 3702.AT2G30670.1; -.
DR iPTMnet; O49332; -.
DR PaxDb; O49332; -.
DR PRIDE; O49332; -.
DR ProteomicsDB; 232410; -.
DR EnsemblPlants; AT2G30670.1; AT2G30670.1; AT2G30670.
DR GeneID; 817617; -.
DR Gramene; AT2G30670.1; AT2G30670.1; AT2G30670.
DR KEGG; ath:AT2G30670; -.
DR Araport; AT2G30670; -.
DR TAIR; locus:2054447; AT2G30670.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_1_1; -.
DR InParanoid; O49332; -.
DR OMA; AVEWVGF; -.
DR OrthoDB; 1074094at2759; -.
DR PhylomeDB; O49332; -.
DR BioCyc; ARA:AT2G30670-MON; -.
DR PRO; PR:O49332; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O49332; baseline and differential.
DR Genevisible; O49332; AT.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR InterPro; IPR045000; TR.
DR PANTHER; PTHR42898; PTHR42898; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW NADP; Oxidoreductase; Reference proteome.
FT CHAIN 1..262
FT /note="Tropinone reductase homolog At2g30670"
FT /id="PRO_0000432369"
FT ACT_SITE 159
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT BINDING 13..37
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250|UniProtKB:P50162"
FT BINDING 146
FT /ligand="substrate"
FT /evidence="ECO:0000250|UniProtKB:P50162"
SQ SEQUENCE 262 AA; 28026 MW; 985B8835C8559436 CRC64;
MDKRWSLQGM TALVTGGASG IGHAIVEELA GLGARIYVCD ISETLLNQSL SEWEKKGFQV
SGSICDVSSH SERETLMQTV SKMFDGKLNI LVNNVGVVNP KPTIEYVAAD FSFSISTNLE
SAYHLSQLSH PLLKASEFGS IIFISSVGGV VSMECGSIYS LTKGALNQLA KTLACEWARD
GIRANSVAPN FIYTAMAQPF FKDADYEKSL VSRTPLGRAG EPNEVSSLVA FLCLPAASYI
TGQTICVDGG LTVNGFSYKP QA
