BZIP8_CAEEL
ID BZIP8_CAEEL Reviewed; 176 AA.
AC P46505; Q8IG25;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=bZIP transcription factor 8;
GN Name=zip-8; ORFNames=F23F12.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=P46505-1; Sequence=Displayed;
CC Name=b;
CC IsoId=P46505-2; Sequence=VSP_046485;
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; FO081210; CCD69928.1; -; Genomic_DNA.
DR EMBL; FO081210; CCD69929.1; -; Genomic_DNA.
DR PIR; F88484; F88484.
DR RefSeq; NP_498426.1; NM_066025.3. [P46505-1]
DR RefSeq; NP_871665.1; NM_181936.4. [P46505-2]
DR AlphaFoldDB; P46505; -.
DR SMR; P46505; -.
DR BioGRID; 41142; 6.
DR IntAct; P46505; 4.
DR MINT; P46505; -.
DR STRING; 6239.F23F12.9a; -.
DR PaxDb; P46505; -.
DR PeptideAtlas; P46505; -.
DR EnsemblMetazoa; F23F12.9a.1; F23F12.9a.1; WBGene00017755. [P46505-1]
DR EnsemblMetazoa; F23F12.9b.1; F23F12.9b.1; WBGene00017755. [P46505-2]
DR GeneID; 175924; -.
DR KEGG; cel:CELE_F23F12.9; -.
DR UCSC; F23F12.9a; c. elegans.
DR CTD; 175924; -.
DR WormBase; F23F12.9a; CE01256; WBGene00017755; zip-8. [P46505-1]
DR WormBase; F23F12.9b; CE32389; WBGene00017755; zip-8. [P46505-2]
DR eggNOG; KOG3119; Eukaryota.
DR HOGENOM; CLU_1596060_0_0_1; -.
DR InParanoid; P46505; -.
DR OMA; NIAMREM; -.
DR PhylomeDB; P46505; -.
DR SignaLink; P46505; -.
DR PRO; PR:P46505; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00017755; Expressed in embryo and 3 other tissues.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF07716; bZIP_2; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..176
FT /note="bZIP transcription factor 8"
FT /id="PRO_0000076647"
FT DOMAIN 65..128
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 44..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..92
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 100..107
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT COMPBIAS 56..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 68..176
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_046485"
SQ SEQUENCE 176 AA; 20468 MW; 96C763D2618E0434 CRC64;
MSNTMQGAHY PQMAFDPTWQ MHPAYATATA FNPYNVSFDF TRSPNTSGGS DESMSDGSKI
DPKRSPKYLE KRMKNNEAAK KSRASRKHRE QKNQTENELL KRKNAALEEE LKQAKCELAQ
MQITIRDMSI EREAYRRENE MLKMVNNKFA DSKFEPPQPL RDMTNCNLPY KYELLS
