ID   TROD_TREPA              Reviewed;         367 AA.
AC   P96119; O83198;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=Zinc transport system membrane protein TroD;
GN   Name=troD; OrderedLocusNames=TP_0166;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9332349; DOI=10.1016/s0378-1119(97)00234-5;
RA   Hardham J.M., Stamm L.V., Porcella S.F., Frye J.G., Barnes N.Y.,
RA   Howell J.K., Mueller S.L., Radolf J.D., Weinstock G.M., Norris S.J.;
RT   "Identification and transcriptional analysis of a Treponema pallidum operon
RT   encoding a putative ABC transport system, an iron-activated repressor
RT   protein homolog, and a glycolytic pathway enzyme homolog.";
RL   Gene 197:47-64(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Part of an ATP-driven transport system TroABCD for zinc.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ABC-3 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; U55214; AAC45728.1; -; Genomic_DNA.
DR   EMBL; AE000520; AAC65156.1; -; Genomic_DNA.
DR   PIR; C71357; C71357.
DR   RefSeq; WP_014342310.1; NC_021490.2.
DR   AlphaFoldDB; P96119; -.
DR   SMR; P96119; -.
DR   STRING; 243276.TPANIC_0166; -.
DR   TCDB; 3.A.1.15.8; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAC65156; AAC65156; TP_0166.
DR   GeneID; 57878708; -.
DR   KEGG; tpa:TP_0166; -.
DR   eggNOG; COG1108; Bacteria.
DR   HOGENOM; CLU_028808_4_1_12; -.
DR   OMA; ALMGDGI; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3470.10; -; 1.
DR   InterPro; IPR037294; ABC_BtuC-like.
DR   InterPro; IPR001626; ABC_TroCD.
DR   PANTHER; PTHR30477; PTHR30477; 1.
DR   Pfam; PF00950; ABC-3; 1.
DR   SUPFAM; SSF81345; SSF81345; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..367
FT                   /note="Zinc transport system membrane protein TroD"
FT                   /id="PRO_0000171155"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   367 AA;  38764 MW;  991A23737DD6B900 CRC64;
     MTMEVVLIAV VVSVACALCG VFLVLRRISL MSDAISHSVI LGIVLGYFLS RTLSSFVPFV
     GAVIAGICSV ICAELLQKTG MVKSDAAVGL VFPAMFGLGV ILVSLYAGNV HLDTDAVLLG
     EIGLAPLDRV SFFAWSLPRS LVQMGSVLCG LLLLLALFFK ELKISTFDPV LATSLGFSPT
     LINYGLMLAV SITCVGAFDS VGAVLVIALM ITPPAAALLL TDNLLLMLVL ASLLASCASI
     SGLFLAVKID GSIAGAMATM AGVLFALVYL FSPKHGVVRR CLVMRALKLD LDVVTLAVHL
     ATHRYTVERS VECAEVHLTE HVSWSARRAA RVVRTALRRG MVERHGALLL LTAQGVSLAQ
     ARLDVSV