ID   TRP2_RHYMA              Reviewed;          17 AA.
AC   P81733; P81734;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Tachykinin-related peptide 2;
DE            Short=LemTRP 2;
DE   Contains:
DE     RecName: Full=Tachykinin-related peptide 1;
DE              Short=LemTRP 1;
OS   Rhyparobia maderae (Madeira cockroach) (Leucophaea maderae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blaberoidea; Blaberidae;
OC   Oxyhaloinae; Rhyparobia.
OX   NCBI_TaxID=36963;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT ARG-17.
RC   TISSUE=Midgut;
RX   PubMed=8897641; DOI=10.1016/0167-0115(96)00092-4;
RA   Muren J.E., Naessel D.R.;
RT   "Isolation of five tachykinin-related peptides from the midgut of the
RT   cockroach Leucophaea maderae: existence of N-terminally extended
RT   isoforms.";
RL   Regul. Pept. 65:185-196(1996).
RN   [2]
RP   CHARACTERIZATION, AND MASS SPECTROMETRY.
RC   TISSUE=Brain;
RX   PubMed=9114447; DOI=10.1016/s0196-9781(96)00243-4;
RA   Muren J.E., Naessel D.R.;
RT   "Seven tachykinin-related peptides isolated from the brain of the madeira
RT   cockroach; evidence for tissue-specific expression of isoforms.";
RL   Peptides 18:7-15(1997).
CC   -!- FUNCTION: Myoactive peptide. Increases the amplitude and frequency of
CC       spontaneous contractions and tonus of hindgut muscle.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Midgut and brain.
CC   -!- MASS SPECTROMETRY: [Tachykinin-related peptide 2]: Mass=1796.4;
CC       Method=MALDI; Evidence={ECO:0000269|PubMed:9114447};
CC   -!- MASS SPECTROMETRY: [Tachykinin-related peptide 1]: Mass=903.1;
CC       Method=MALDI; Evidence={ECO:0000269|PubMed:9114447};
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DR   AlphaFoldDB; P81733; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Cleavage on pair of basic residues; Direct protein sequencing;
KW   Neuropeptide; Secreted.
FT   PEPTIDE         1..17
FT                   /note="Tachykinin-related peptide 2"
FT                   /id="PRO_0000033574"
FT   PEPTIDE         9..17
FT                   /note="Tachykinin-related peptide 1"
FT                   /id="PRO_0000033575"
FT   MOD_RES         17
FT                   /note="Arginine amide"
FT                   /evidence="ECO:0000269|PubMed:8897641"
SQ   SEQUENCE   17 AA;  1798 MW;  48577A957F4221F3 CRC64;
     APEESPKRAP SGFLGVR