TRP8_RHOPR
ID TRP8_RHOPR Reviewed; 12 AA.
AC P85809;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 11-DEC-2019, entry version 16.
DE RecName: Full=Tachykinin-related peptide 8 {ECO:0000303|PubMed:19137558};
DE Short=Rhopr-TRP-8 {ECO:0000303|PubMed:19137558};
DE Contains:
DE RecName: Full=Tachykinin-related peptide 8(8-12) {ECO:0000303|PubMed:19137558};
DE Short=Rhopr-TRP-8(8-12) {ECO:0000303|PubMed:19137558};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, MASS SPECTROMETRY, PYROGLUTAMATE FORMATION AT GLN-1, AND
RP AMIDATION AT ARG-12.
RC TISSUE=Brain {ECO:0000269|PubMed:19137558};
RX PubMed=19137558; DOI=10.1002/pmic.200800499;
RA Ons S., Richter F., Urlaub H., Pomar R.R.;
RT "The neuropeptidome of Rhodnius prolixus brain.";
RL Proteomics 9:788-792(2009).
CC -!- FUNCTION: Myoactive peptide. Increases the amplitude and frequency of
CC spontaneous contractions and tonus of hindgut muscle. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- MASS SPECTROMETRY: [Tachykinin-related peptide 8]: Mass=1419.72;
CC Method=MALDI; Evidence={ECO:0000269|PubMed:19137558};
CC -!- MASS SPECTROMETRY: [Tachykinin-related peptide 8(8-12)]: Mass=608.33;
CC Method=MALDI; Evidence={ECO:0000269|PubMed:19137558};
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DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide;
KW Pyrrolidone carboxylic acid; Reference proteome; Secreted.
FT PEPTIDE 1..12
FT /note="Tachykinin-related peptide 8"
FT /evidence="ECO:0000269|PubMed:19137558"
FT /id="PRO_0000365759"
FT PEPTIDE 8..12
FT /note="Tachykinin-related peptide 8(8-12)"
FT /evidence="ECO:0000269|PubMed:19137558"
FT /id="PRO_0000365760"
FT MOD_RES 1
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:19137558"
FT MOD_RES 12
FT /note="Arginine amide"
FT /evidence="ECO:0000269|PubMed:19137558"
SQ SEQUENCE 12 AA; 1438 MW; C6DB57379CC8769D CRC64;
QERRAMGFVG MR