BZP14_PHATC
ID BZP14_PHATC Reviewed; 468 AA.
AC B7FX91;
DT 22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=bZIP transcription factor 14 {ECO:0000305};
GN Name=bZIP14 {ECO:0000303|PubMed:28420744};
GN ORFNames=PHATRDRAFT_45314 {ECO:0000312|EMBL:EEC49336.1};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484 {ECO:0000312|Proteomes:UP000000759};
RN [1] {ECO:0000312|Proteomes:UP000000759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1 {ECO:0000312|Proteomes:UP000000759};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2] {ECO:0000312|Proteomes:UP000000759}
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1 {ECO:0000312|Proteomes:UP000000759};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000305}
RP FUNCTION, AND INDUCTION.
RX PubMed=28420744; DOI=10.15252/embj.201696392;
RA Matthijs M., Fabris M., Obata T., Foubert I., Franco-Zorrilla J.M.,
RA Solano R., Fernie A.R., Vyverman W., Goossens A.;
RT "The transcription factor bZIP14 regulates the TCA cycle in the diatom
RT Phaeodactylum tricornutum.";
RL EMBO J. 36:1559-1576(2017).
CC -!- FUNCTION: Transcriptional activator which binds to the C-box-like motif
CC 5'-TGACGT-3' and A-box-like motif 5'-GTACGTA-3' of target promoters to
CC positively regulate the expression of genes involved in the
CC tricarboxylic acid (TCA) cycle in response to nitrogen starvation
CC (PubMed:28420744). May also regulate the TCA cycle during day-to-night
CC transitions (PubMed:28420744). {ECO:0000269|PubMed:28420744}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- INDUCTION: By nitrogen deficiency. {ECO:0000269|PubMed:28420744}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; CM000609; EEC49336.1; -; Genomic_DNA.
DR RefSeq; XP_002179513.1; XM_002179477.1.
DR AlphaFoldDB; B7FX91; -.
DR SMR; B7FX91; -.
DR GeneID; 7200016; -.
DR KEGG; pti:PHATRDRAFT_45314; -.
DR eggNOG; ENOG502S7C7; Eukaryota.
DR HOGENOM; CLU_777225_0_0_1; -.
DR InParanoid; B7FX91; -.
DR OrthoDB; 1498935at2759; -.
DR Proteomes; UP000000759; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006995; P:cellular response to nitrogen starvation; IMP:UniProtKB.
DR GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 2.
DR SUPFAM; SSF57959; SSF57959; 2.
DR PROSITE; PS50217; BZIP; 2.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..468
FT /note="bZIP transcription factor 14"
FT /id="PRO_0000449325"
FT DOMAIN 117..165
FT /note="bZIP 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT DOMAIN 279..333
FT /note="bZIP 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 55..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..139
FT /note="Basic motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 145..159
FT /note="Leucine-zipper 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 234..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..312
FT /note="Basic motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 313..320
FT /note="Leucine-zipper 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 400..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 51937 MW; A2F7059CF4E65BB1 CRC64;
MRFPAASVAV DSTPQLRLLQ MKDSHETYST VQLVHSPLPE KGPNSVLVDV PQQISRRKPT
AEQSFVSGSD SSRSSTKSSS GSRPVMTTTA DPNIVTAAST ESVSSSPKWL PKKADTDDRV
QRSRERNRIH ARKTRQRKKE QMQSLEGRAT DLKHEQIRLK QIINEKNTAN ILVGLFSKGQ
SQSPNEDPRV EALMYRSVEE IPDPSKIPEL PALILPGQHA SKKIKVAVPV VAASPQSMSD
GGGEEVASTS DVSGDEQQVP DDGIDYDLLG KDRSKCTPEE LDQIRRERNR MHAKRTRDRK
RIFTEEMAEM CRILEEENHL LRVHLGGLDS DFKSESTTTS THVVDRIDSV LSTPTLASCA
PPQDMVSVSL SPSQLPSKPS TKEVAFNQLQ TLLDVAGSFE RQQREAERKV PQMCSISAAS
DTSTSDSSHH HRQRRCHKGD SDRPVKRQRY QVPRSITTTT SLAAPVGW
