BZP44_ARATH
ID BZP44_ARATH Reviewed; 173 AA.
AC C0Z2L5; Q9FWS7;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=bZIP transcription factor 44 {ECO:0000305};
DE Short=AtbZIP44 {ECO:0000303|PubMed:11906833};
GN Name=BZIP44 {ECO:0000303|PubMed:11906833};
GN OrderedLocusNames=At1g75390 {ECO:0000312|Araport:AT1G75390};
GN ORFNames=F1B16.8 {ECO:0000312|EMBL:AAG13064.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-173.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11906833; DOI=10.1016/s1360-1385(01)02223-3;
RA Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J.,
RA Tiedemann J., Kroj T., Parcy F.;
RT "bZIP transcription factors in Arabidopsis.";
RL Trends Plant Sci. 7:106-111(2002).
RN [7]
RP INTERACTION WITH BZIP1; BZIP9; BZIP10; BZIP25 AND BZIP63.
RX PubMed=16709202; DOI=10.1111/j.1365-313x.2006.02731.x;
RA Ehlert A., Weltmeier F., Wang X., Mayer C.S., Smeekens S.,
RA Vicente-Carbajosa J., Droege-Laser W.;
RT "Two-hybrid protein-protein interaction analysis in Arabidopsis
RT protoplasts: establishment of a heterodimerization map of group C and group
RT S bZIP transcription factors.";
RL Plant J. 46:890-900(2006).
RN [8]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=23461773; DOI=10.1111/tpj.12162;
RA Iglesias-Fernandez R., Barrero-Sicilia C., Carrillo-Barral N.,
RA Onate-Sanchez L., Carbonero P.;
RT "Arabidopsis thaliana bZIP44: a transcription factor affecting seed
RT germination and expression of the mannanase-encoding gene AtMAN7.";
RL Plant J. 74:767-780(2013).
CC -!- FUNCTION: Transcription factor that binds to the DNA G-box motif 5'-
CC CACGTG-3' of MAN7 promoter. Involved in the positive regulation of seed
CC germination through MAN7 gene activation. MAN7 is required for both,
CC loosening of the micropylar endosperm, and rupture of the seed coat in
CC germinating seeds. {ECO:0000269|PubMed:23461773}.
CC -!- SUBUNIT: Forms heterodimers with BZIP1, BZIP9, BZIP10, BZIP25 and
CC BZIP63. {ECO:0000269|PubMed:16709202}.
CC -!- INTERACTION:
CC C0Z2L5; Q9FGX2: BZIP1; NbExp=5; IntAct=EBI-942804, EBI-942623;
CC C0Z2L5; O22763: BZIP10; NbExp=3; IntAct=EBI-942804, EBI-942648;
CC C0Z2L5; Q9M1G6: BZIP25; NbExp=6; IntAct=EBI-942804, EBI-942696;
CC C0Z2L5; Q9LZP8: BZIP53; NbExp=3; IntAct=EBI-942804, EBI-942845;
CC C0Z2L5; O81002: bZIP6; NbExp=3; IntAct=EBI-942804, EBI-3133475;
CC C0Z2L5; B9DGI8: BZIP63; NbExp=4; IntAct=EBI-942804, EBI-942713;
CC C0Z2L5; B9DGI8-2: BZIP63; NbExp=3; IntAct=EBI-942804, EBI-15191817;
CC C0Z2L5; Q9FUD3: BZIP9; NbExp=3; IntAct=EBI-942804, EBI-942633;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences. {ECO:0000305};
CC Name=1;
CC IsoId=C0Z2L5-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in the micropylar endosperm and radicle
CC tip in early germinating seeds. {ECO:0000269|PubMed:23461773}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but seeds have decreased germination speed after
CC imbibition, without affecting overall germination rate.
CC {ECO:0000269|PubMed:23461773}.
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DR EMBL; AC023754; AAG13064.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35713.1; -; Genomic_DNA.
DR EMBL; AK318829; BAH56944.1; -; mRNA.
DR EMBL; AK318991; BAH57106.1; -; mRNA.
DR EMBL; AB493534; BAH30372.1; -; Genomic_DNA.
DR EMBL; BT004768; AAO44034.1; -; mRNA.
DR PIR; D96784; D96784.
DR RefSeq; NP_177672.2; NM_106193.4. [C0Z2L5-1]
DR AlphaFoldDB; C0Z2L5; -.
DR SMR; C0Z2L5; -.
DR IntAct; C0Z2L5; 12.
DR MINT; C0Z2L5; -.
DR STRING; 3702.AT1G75390.1; -.
DR PaxDb; C0Z2L5; -.
DR PRIDE; C0Z2L5; -.
DR EnsemblPlants; AT1G75390.1; AT1G75390.1; AT1G75390. [C0Z2L5-1]
DR GeneID; 843875; -.
DR Gramene; AT1G75390.1; AT1G75390.1; AT1G75390. [C0Z2L5-1]
DR KEGG; ath:AT1G75390; -.
DR Araport; AT1G75390; -.
DR TAIR; locus:2018411; AT1G75390.
DR eggNOG; ENOG502S0BS; Eukaryota.
DR HOGENOM; CLU_112634_1_0_1; -.
DR InParanoid; C0Z2L5; -.
DR OMA; GVFENDH; -.
DR PhylomeDB; C0Z2L5; -.
DR PRO; PR:C0Z2L5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; C0Z2L5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IMP:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0009845; P:seed germination; IMP:TAIR.
DR CDD; cd14702; bZIP_plant_GBF1; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR045314; bZIP_plant_GBF1.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..173
FT /note="bZIP transcription factor 44"
FT /id="PRO_0000436841"
FT DOMAIN 39..102
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 41..62
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 67..81
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 173 AA; 19073 MW; 5B91C5D31304EAEF CRC64;
MNNKTEMGSS TSGNCSSVST TGLANSGSES DLRQRDLIDE RKRKRKQSNR ESARRSRMRK
QKHLDDLTAQ VTHLRKENAQ IVAGIAVTTQ HYVTIEAEND ILRAQVLELN HRLQSLNEIV
DFVESSSSGF GMETGQGLFD GGLFDGVMNP MNLGFYNQPI MASASTAGDV FNC
