BZP60_ORYSJ
ID BZP60_ORYSJ Reviewed; 568 AA.
AC Q8LIB3;
DT 30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=bZIP transcription factor 60 {ECO:0000303|PubMed:18065552};
DE Short=OsbZIP60 {ECO:0000303|PubMed:18065552};
GN Name=BZIP60 {ECO:0000303|PubMed:18065552};
GN OrderedLocusNames=Os07g0644100 {ECO:0000312|EMBL:BAF22360.1},
GN LOC_Os07g44950 {ECO:0000305};
GN ORFNames=OJ1003_C06.133 {ECO:0000312|EMBL:BAD30259.1},
GN OJ1458_B07.101 {ECO:0000312|EMBL:BAC07004.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18065552; DOI=10.1104/pp.107.112821;
RA Nijhawan A., Jain M., Tyagi A.K., Khurana J.P.;
RT "Genomic survey and gene expression analysis of the basic leucine zipper
RT transcription factor family in rice.";
RL Plant Physiol. 146:333-350(2008).
RN [6]
RP FUNCTION, AND INDUCTION.
RX PubMed=22050533; DOI=10.1111/j.1365-313x.2011.04844.x;
RA Hayashi S., Wakasa Y., Takahashi H., Kawakatsu T., Takaiwa F.;
RT "Signal transduction by IRE1-mediated splicing of bZIP50 and other stress
RT sensors in the endoplasmic reticulum stress response of rice.";
RL Plant J. 69:946-956(2012).
RN [7]
RP SUBCELLULAR LOCATION.
RX PubMed=24153418; DOI=10.1093/jxb/ert312;
RA Ohta M., Wakasa Y., Takahashi H., Hayashi S., Kudo K., Takaiwa F.;
RT "Analysis of rice ER-resident J-proteins reveals diversity and functional
RT differentiation of the ER-resident Hsp70 system in plants.";
RL J. Exp. Bot. 64:5429-5441(2013).
CC -!- FUNCTION: Transcription factor involved in endoplasmic reticulum (ER)
CC stress response. Acts as ER stress sensor and activates the
CC transcription factor BZIP50 and the chaperone BIP1.
CC {ECO:0000269|PubMed:22050533}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000305|PubMed:24153418}; Single-pass membrane protein
CC {ECO:0000255}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978,
CC ECO:0000305|PubMed:24153418}. Note=The bZIP domain is translocated into
CC the nucleus in response to ER stress. {ECO:0000305|PubMed:24153418}.
CC -!- INDUCTION: By dithiothreitol- and tunicamycin-induced endoplasmic
CC reticulum (ER) stress response. {ECO:0000305|PubMed:22050533}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AP003765; BAD30259.1; -; Genomic_DNA.
DR EMBL; AP003832; BAC07004.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF22360.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT02885.1; -; Genomic_DNA.
DR EMBL; AK121898; BAH00712.1; -; mRNA.
DR RefSeq; XP_015647746.1; XM_015792260.1.
DR AlphaFoldDB; Q8LIB3; -.
DR SMR; Q8LIB3; -.
DR STRING; 4530.OS07T0644100-01; -.
DR PaxDb; Q8LIB3; -.
DR PRIDE; Q8LIB3; -.
DR EnsemblPlants; Os07t0644100-01; Os07t0644100-01; Os07g0644100.
DR GeneID; 4344086; -.
DR Gramene; Os07t0644100-01; Os07t0644100-01; Os07g0644100.
DR KEGG; osa:4344086; -.
DR eggNOG; ENOG502QQUV; Eukaryota.
DR HOGENOM; CLU_018118_2_0_1; -.
DR InParanoid; Q8LIB3; -.
DR OMA; HGERDSC; -.
DR OrthoDB; 849173at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; IBA:GO_Central.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:UniProtKB.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Endoplasmic reticulum; Glycoprotein; Membrane; Nucleus;
KW Reference proteome; Transcription; Transcription regulation; Transmembrane;
KW Transmembrane helix; Unfolded protein response.
FT CHAIN 1..568
FT /note="bZIP transcription factor 60"
FT /id="PRO_0000438370"
FT TOPO_DOM 1..240
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 262..568
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT DOMAIN 111..171
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 45..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..144
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 150..157
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 479..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 307
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 452
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 456
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 488
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 499
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 568 AA; 60072 MW; 0E85546CD9D928CA CRC64;
MAEPDLLAPF ADLPFPPGDD FPDFPTLGDD AFALEDFDLD DLDFDFDVDL FPPDAPPPVT
TSSSSSAAGS PEAGTSSAGD GGSKNEESAD SSSPSRSGSD GGGGKDGKDD EAKRRARLVR
NRESAHQSRQ RKKQYVEELE GKVKVMQATI ADLTARISCV TAENAALKQQ LGGAAGAGAA
APPPPMPMYP AVYPLPMPWI HPAYAMRGSQ VPLVPIPRLK TQQPASTPEP PAKKARKTKK
VAGVSLLGLL FLMMVCGCLV PAVNRMYGAA YTGEGAAIVP SHHGRILAVE GPQNSVSNGV
DPKVPQNGSE TLPALLYLPR NGKHVKINGN LVIKSIVASE KASSRLSNYG EKGSGNQGKE
ETSLAIPGYV APLEAGEVMD SAKGMNELMA LAPGDGSIYR EDDGMLPQWF SEAMSGPMLN
SGMCTEVFQF DLSPTTADAN GIVPVYSGSV TNTSQNYTEN LPSGPVQKVK NRRISYSEAI
PLRGSTSNDT DHFKAPPKNH SQSHAGRKPV SSVVVSVLAD PREASDRDGE GRISSNSLSR
IFVVVLIDSV KYVTYSCVLP FKSHSPHL
