BZP61_ARATH
ID BZP61_ARATH Reviewed; 329 AA.
AC Q9M2K4;
DT 01-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Basic leucine zipper 61 {ECO:0000303|PubMed:11906833};
DE Short=AtbZIP61 {ECO:0000303|PubMed:11906833};
DE Short=bZIP protein 61;
GN Name=BZIP61 {ECO:0000303|PubMed:11906833}; OrderedLocusNames=At3g58120;
GN ORFNames=F9D24.30;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia; TISSUE=Flower, and Silique;
RA Tiedemann J.;
RT "The family of bZIP transcription factors in Arabidopsis thaliana.";
RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11906833; DOI=10.1016/s1360-1385(01)02223-3;
RA Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J.,
RA Tiedemann J., Kroj T., Parcy F.;
RT "bZIP transcription factors in Arabidopsis.";
RL Trends Plant Sci. 7:106-111(2002).
RN [5]
RP FUNCTION, INTERACTION WITH BZIP43 AND VIP1/BZIP51, SUBCELLULAR LOCATION,
RP AND MUTAGENESIS OF PRO-246.
RX PubMed=17719007; DOI=10.1016/j.bbrc.2007.08.026;
RA Shen H., Cao K., Wang X.;
RT "A conserved proline residue in the leucine zipper region of AtbZIP34 and
RT AtbZIP61 in Arabidopsis thaliana interferes with the formation of
RT homodimer.";
RL Biochem. Biophys. Res. Commun. 362:425-430(2007).
RN [6]
RP SUBUNIT, AND INTERACTION WITH BZIP18.
RX PubMed=27896439; DOI=10.1007/s00497-016-0295-5;
RA Gibalova A., Steinbachova L., Hafidh S., Blahova V., Gadiou Z.,
RA Michailidis C., Muller K., Pleskot R., Duplakova N., Honys D.;
RT "Characterization of pollen-expressed bZIP protein interactions and the
RT role of ATbZIP18 in the male gametophyte.";
RL Plant Reprod. 30:1-17(2017).
CC -!- FUNCTION: Transcriptional activator. {ECO:0000269|PubMed:17719007}.
CC -!- SUBUNIT: Forms heterodimers with BZIP18, BZIP43 and VIP1/BZIP51.
CC {ECO:0000269|PubMed:17719007, ECO:0000269|PubMed:27896439}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978,
CC ECO:0000269|PubMed:17719007}.
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DR EMBL; AF401300; AAK84223.1; -; mRNA.
DR EMBL; AL137081; CAB68150.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79744.1; -; Genomic_DNA.
DR EMBL; AY093053; AAM13052.1; -; mRNA.
DR EMBL; AY087356; AAM64906.1; -; mRNA.
DR EMBL; BT008728; AAP42741.1; -; mRNA.
DR PIR; T45972; T45972.
DR RefSeq; NP_191371.1; NM_115674.4.
DR AlphaFoldDB; Q9M2K4; -.
DR SMR; Q9M2K4; -.
DR BioGRID; 10296; 14.
DR IntAct; Q9M2K4; 12.
DR STRING; 3702.AT3G58120.1; -.
DR iPTMnet; Q9M2K4; -.
DR PaxDb; Q9M2K4; -.
DR PRIDE; Q9M2K4; -.
DR ProteomicsDB; 239107; -.
DR EnsemblPlants; AT3G58120.1; AT3G58120.1; AT3G58120.
DR GeneID; 824981; -.
DR Gramene; AT3G58120.1; AT3G58120.1; AT3G58120.
DR KEGG; ath:AT3G58120; -.
DR Araport; AT3G58120; -.
DR TAIR; locus:2085425; AT3G58120.
DR eggNOG; ENOG502QQW5; Eukaryota.
DR HOGENOM; CLU_059253_1_0_1; -.
DR InParanoid; Q9M2K4; -.
DR OrthoDB; 1069555at2759; -.
DR PhylomeDB; Q9M2K4; -.
DR PRO; PR:Q9M2K4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M2K4; baseline and differential.
DR Genevisible; Q9M2K4; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR CDD; cd14703; bZIP_plant_RF2; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR044759; bZIP_RF2.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 1: Evidence at protein level;
KW Activator; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..329
FT /note="Basic leucine zipper 61"
FT /id="PRO_0000430353"
FT DOMAIN 202..254
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..223
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 230..251
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 304..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 246
FT /note="P->A: Homodimerization and binding to G-box
FT element."
FT /evidence="ECO:0000269|PubMed:17719007"
SQ SEQUENCE 329 AA; 36805 MW; 15FDD8B08B0FD39F CRC64;
MAQLPPKIPT MTTPNWPDFS SQKLPSIAAT AAAAATAGPQ QQNPSWMDEF LDFSATRRGT
HRRSISDSIA FLEPPSSGVG NHHFDRFDDE QFMSMFNDDV HNNNHNHHHH HSINGNVGPT
RSSSNTSTPS DHNSLSDDDN NKEAPPSDHD HHMDNNVANQ NNAAGNNYNE SDEVQSQCKT
EPQDGPSANQ NSGGSSGNRI HDPKRVKRIL ANRQSAQRSR VRKLQYISEL ERSVTSLQTE
VSVLSPRVAF LDHQRLLLNV DNSAIKQRIA ALAQDKIFKD AHQEALKREI ERLRQVYHQQ
SLKKMENNVS DQSPADIKPS VEKEQLLNV
