BZPC_DICDI
ID BZPC_DICDI Reviewed; 804 AA.
AC Q54WU0;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Probable basic-leucine zipper transcription factor C;
GN Name=bzpC; ORFNames=DDB_G0279439;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000031; EAL67658.1; -; Genomic_DNA.
DR RefSeq; XP_641627.1; XM_636535.1.
DR AlphaFoldDB; Q54WU0; -.
DR SMR; Q54WU0; -.
DR STRING; 44689.DDB0220096; -.
DR PaxDb; Q54WU0; -.
DR EnsemblProtists; EAL67658; EAL67658; DDB_G0279439.
DR GeneID; 8622033; -.
DR KEGG; ddi:DDB_G0279439; -.
DR dictyBase; DDB_G0279439; bzpC.
DR eggNOG; ENOG502SEPJ; Eukaryota.
DR HOGENOM; CLU_350377_0_0_1; -.
DR InParanoid; Q54WU0; -.
DR OMA; ERKATHV; -.
DR Reactome; R-DDI-381033; ATF6 (ATF6-alpha) activates chaperones.
DR PRO; PR:Q54WU0; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..804
FT /note="Probable basic-leucine zipper transcription factor
FT C"
FT /id="PRO_0000384403"
FT DOMAIN 415..478
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 86..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..436
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 443..450
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 670..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 90842 MW; 717F5BC9DB57194E CRC64;
MGDFNSNEDN NNPFNNVLYN PYIVDLYDTT NNNNNNNNNN NIISGFNCDS SIFTQQISNT
NNELTIPLTQ SIQNLLPPVQ QQTQLFISPN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
NNNNNNNNNN NNNNNNNNNN NNNNNDINTS IDINLNQLVY STPSQQITNS VQPIYQCATQ
STTSNIDTNI NTINDNNNNN NNNNNNNNNS VNNNLLSMCQ DPTLILQIQQ LLLQQQLLQQ
AQQQSVPLNI QVPTTTTPIN QQHQALLVPQ QKQFYGNVSD NSSPETNFSY ASPSSPSSTQ
SQSSPYEQQP LSPNPTISLS SSISVTATTT TRPNATEKTK ESSLKSKSKS NEKDKEREDE
EEDDDDRPKK RKKFDKNVYK GVDLGDELLE ITSEEFQAYK NNFFANASDK KTVSALNYQF
RKIKNRESAR RSRERKATHV DELEAKIAEI EKERDNYKKE NERLRMELDQ YKLQEKQKSA
GSIFDYISIG SPTTQNFSKN FGIILFLFLF GSFILTNTTP NFFNTNNGVI NPNLVYNANS
NNNNNNNNNV NRFSVNGVHS TQQYFQSQRN PLSNLDEDSL ESLTASQGVF STHFVPEQPS
ILLNRESIRN WATLPQNSVA SLSFEKDNAL KTIENANLDK SKHNVISNLN QLQQQQPSSD
ELMIDQKEEK NCNNNNENNN NNDNNKNSDD EKGKEIEEIK RKSTTTTISP TRYVNNSTIS
LLVNPTSVIG DIPDDLMKNS NVTTFGENSS FKFNFLIDTQ NFPNGSNDIS KAFFDNENQQ
MTVTSVIIAI QKSPKTPSQQ PSTK
