BZPD_DICDI
ID BZPD_DICDI Reviewed; 834 AA.
AC Q54Y73;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Probable basic-leucine zipper transcription factor D;
GN Name=bzpD; ORFNames=DDB_G0278379;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000023; EAL68362.1; -; Genomic_DNA.
DR RefSeq; XP_642329.1; XM_637237.1.
DR AlphaFoldDB; Q54Y73; -.
DR SMR; Q54Y73; -.
DR STRING; 44689.DDB0220090; -.
DR PaxDb; Q54Y73; -.
DR EnsemblProtists; EAL68362; EAL68362; DDB_G0278379.
DR GeneID; 8621535; -.
DR KEGG; ddi:DDB_G0278379; -.
DR dictyBase; DDB_G0278379; bzpD.
DR eggNOG; ENOG502RSPE; Eukaryota.
DR HOGENOM; CLU_340528_0_0_1; -.
DR InParanoid; Q54Y73; -.
DR OMA; FATANDH; -.
DR PRO; PR:Q54Y73; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..834
FT /note="Probable basic-leucine zipper transcription factor
FT D"
FT /id="PRO_0000384404"
FT DOMAIN 391..454
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 83..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..402
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 407..414
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 455..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 211..246
FT /evidence="ECO:0000255"
FT COMPBIAS 383..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 93067 MW; 116261474F4D7C48 CRC64;
MDIDYENEIS IVLEAKHNQH LNNNNNGCGN ANNINNENNF LQDDLVYNFL SDEVTLGSDC
TTPYTLNNNH IVNSNYIINN NNNNNNMLND HSSSPMRVPN SSPSLYNNSI ESPELVYHDN
SNNNNNNNNN INVNDINVND INSNSTNNNE SNNNSSSEGE LPCLVDIQQY QYQDMLPFDQ
QPVVVMQNPI ITTTTTTTTT TATIEQQINP SEQQQQQQQQ QQQQQQQQQQ QQQQQQQHQH
LLQEHQHVVN EEVLHMIDPS VDLTNTYMDA AGISDIIASD SSTTTSPSSP STSNMFLTPM
VTTTTTSETS SSSDSSVNII PNNTNTITNI LIKEEDTNNG NNNKKSKKRT IDSRVQNIVH
PLTREELLKI AGKEPVQVVD PPTHNQEDER NVKKQRRLIK NRESAQLSRM RKKIYIEDLE
KTISDLTQDN SSLKEEVLYL QGLVKQLAAQ NSNSNNNSVI DINNNNVNNS QQQQQQHQQQ
QQLNNSNNNN NNNNNNSTNK QQQSKNVKAA GVCLLLIFFS LGVFFQPPQS STQRFGAITS
FDVKPTHSIL SMSDSESSPQ KSLRLSSNHH SLPDGTFNTI PIDQQTTATT NTKSLPSYVL
NNNDDSDSDY ENVNINNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NIKRKQHQQN
PQSDSFQNRK KIKINLATEN TEGDGPLVSK SSATTTTTTT TTTTTSTPKT PQISEDVSID
EIEEPMVHSS QQYIVCSDSP RIVSNNITQT TESLLNSNST NPITIGLLLP AESLNLHNIV
NNIGGGERSI LEISCQVSNI RVWNPLSIDI DHQSSIVPAS SSSSSASSIF TNHF
