BZPF_DICDI
ID BZPF_DICDI Reviewed; 631 AA.
AC Q54WN7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Probable basic-leucine zipper transcription factor F;
GN Name=bzpF; ORFNames=DDB_G0279529;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000031; EAL67703.1; -; Genomic_DNA.
DR RefSeq; XP_641680.1; XM_636588.1.
DR AlphaFoldDB; Q54WN7; -.
DR SMR; Q54WN7; -.
DR STRING; 44689.DDB0220091; -.
DR PaxDb; Q54WN7; -.
DR PRIDE; Q54WN7; -.
DR EnsemblProtists; EAL67703; EAL67703; DDB_G0279529.
DR GeneID; 8622088; -.
DR KEGG; ddi:DDB_G0279529; -.
DR dictyBase; DDB_G0279529; bzpF.
DR eggNOG; ENOG502R162; Eukaryota.
DR HOGENOM; CLU_433775_0_0_1; -.
DR InParanoid; Q54WN7; -.
DR OMA; NPMIMSA; -.
DR PRO; PR:Q54WN7; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0035497; F:cAMP response element binding; IDA:dictyBase.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:dictyBase.
DR GO; GO:0031154; P:culmination involved in sorocarp development; IEP:dictyBase.
DR GO; GO:0010628; P:positive regulation of gene expression; IMP:dictyBase.
DR GO; GO:0010737; P:protein kinase A signaling; IEP:dictyBase.
DR GO; GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.
DR GO; GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..631
FT /note="Probable basic-leucine zipper transcription factor
FT F"
FT /id="PRO_0000384406"
FT DOMAIN 405..468
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 46..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..427
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 433..440
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 546..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 35..62
FT /evidence="ECO:0000255"
FT COILED 328..366
FT /evidence="ECO:0000255"
FT COMPBIAS 264..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70777 MW; DB434181506BB7B6 CRC64;
MSLIEGDSIY NLFQTQDLGI DFASSIVPDS PNKFKKNANV FNNFQQQQQQ IQQQNKQSNG
LIYNNNNNNN NNNNNNNNNS SSSNNNNNSS SSNNNNNSNN NNQNHNNNNN NQNHNNIQHN
NAQSQVYINH NSNGSQQEEQ LFSIYLQPEK ENELNNSYHD NVNNNNNNNN NNNNNNNNIN
LNHAQQQQQQ HHLPHGQPHN NNNNNQFYQI KNPMEEIYSS NGIVPNQEPN KKVEYMNEPI
KQNHYNIVPE SIFDVPFGVS SQTMLNVPST NNANNNNNNN NNNNNNNKNI NFKQPIQPNQ
LIPIPPHSNQ NNNISLNNNN SNSNSNPNNN NNNSNNISTQ INNLNNNINN QNNQLNGSNN
GKKKEEDKSI KKRKFISSTP VKGENGGTTL IPTTDGGFNM DEERHQKRQR RLVKNREAAQ
LFRQRQKAYI QDLEKKVSDL TGTNSEFRAR VELLNSENKL IREQLLYLRN FVTQAVSFSF
PKGGSNGTNS PSGVADQFLN SILPPGLNSP LPQGILPAGM NLQNPMIMSA IAEAASKNST
FRQNIQGNLL GTPIPSPQSS LTSNSGNNSP NKPLNNNNNN NNINNNNNNN PSSPNNNLNN
NNNISPNSST SHQVPYLPQN TPPQQSTPNQ R
