ID   BZPI_DICDI              Reviewed;         741 AA.
AC   Q54GG8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Probable basic-leucine zipper transcription factor I;
GN   Name=bzpI; ORFNames=DDB_G0290173;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=16410410; DOI=10.1242/dev.02240;
RA   Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT   "bZIP transcription factor interactions regulate DIF responses in
RT   Dictyostelium.";
RL   Development 133:449-458(2006).
CC   -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR   EMBL; AAFI02000158; EAL62358.1; -; Genomic_DNA.
DR   RefSeq; XP_635860.1; XM_630768.1.
DR   AlphaFoldDB; Q54GG8; -.
DR   STRING; 44689.DDB0216260; -.
DR   PaxDb; Q54GG8; -.
DR   PRIDE; Q54GG8; -.
DR   EnsemblProtists; EAL62358; EAL62358; DDB_G0290173.
DR   GeneID; 8627516; -.
DR   KEGG; ddi:DDB_G0290173; -.
DR   dictyBase; DDB_G0290173; bzpI.
DR   HOGENOM; CLU_322745_0_0_1; -.
DR   OMA; NIANRNF; -.
DR   PRO; PR:Q54GG8; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   Pfam; PF07716; bZIP_2; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
DR   PROSITE; PS50217; BZIP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..741
FT                   /note="Probable basic-leucine zipper transcription factor
FT                   I"
FT                   /id="PRO_0000383602"
FT   DOMAIN          429..492
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          153..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          277..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          349..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..432
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          434..441
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   COILED          77..117
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        174..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..390
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   741 AA;  87328 MW;  53CA273D15E8AE70 CRC64;
     MDESFNSILE PENAWLFLFD DVSQLQQLPI VQNNQENFIN SIDFNTGDVT TTNISGLNFQ
     SLEESLNSDT SIENKPQIIE QIQFLQQQQQ QQHDQIQQQL HNFQQQYQQQ YQQRQQQYQQ
     QYQKPYTPPS FIYSEKNDLV PQQQFHLGQE NLQQPPQSLQ QQQQPPSPSS PPQQQQQPQQ
     QLQQLQQQHQ QHQQHQQQPQ FQQLPIQHEL PQQSQLQHIQ IQSQQIPTQP QPQQIQKQIQ
     IEQPQVQVQQ QIQPQQQIQP QQHIQLQQHI QLQQPQIQQQ QLPPQTIQQK EINKKNQSKQ
     SSNSMPLSQQ IFFNTPKLDQ HLLSYFQTQK TNNTINTLNV DQKRDNIEKQ KENTSPPTPS
     SPVPTIINSN STDINQISPS QQQQQQQQQQ QQTTDINKIL TLQQLEQQQL EYQKQQQQQQ
     QFNLTFDDES KKSIKRINQN IANRNFRQRK KDHIKDIEDK MMELTLENEK LKKENESIRQ
     QEHEGGTMAI LKPSPEKKQL MLEIRSIVRQ IGEALKEDNE KNLIYLLHMY HGAVAKRYSS
     IDKDAEQIAS PEIQLRLASI GYVLKSTPFL TNIFQGIESD SWFNLFKEKA NITSQQSVQL
     DIIREKYCEY NLKLLDEIHD LDSEVKKFFF QNIFVFQSYS ISLKTSKPLD LSQQIEFACK
     LKLLKNKFFE NSCLMFETFS SLSKILTPKQ EALLLVEIDI FSCFNLKKFE MITNVWANKS
     KMKKSSDPFK IGDLSQIFEK P