ID   BZPK_DICDI              Reviewed;         650 AA.
AC   Q54T16;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable basic-leucine zipper transcription factor K;
GN   Name=bzpK; ORFNames=DDB_G0282049;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=16410410; DOI=10.1242/dev.02240;
RA   Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT   "bZIP transcription factor interactions regulate DIF responses in
RT   Dictyostelium.";
RL   Development 133:449-458(2006).
CC   -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR   EMBL; AAFI02000044; EAL66446.1; -; Genomic_DNA.
DR   RefSeq; XP_640435.1; XM_635343.1.
DR   AlphaFoldDB; Q54T16; -.
DR   SMR; Q54T16; -.
DR   PaxDb; Q54T16; -.
DR   EnsemblProtists; EAL66446; EAL66446; DDB_G0282049.
DR   GeneID; 8623390; -.
DR   KEGG; ddi:DDB_G0282049; -.
DR   dictyBase; DDB_G0282049; bzpK.
DR   HOGENOM; CLU_421769_0_0_1; -.
DR   InParanoid; Q54T16; -.
DR   PhylomeDB; Q54T16; -.
DR   PRO; PR:Q54T16; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR046347; bZIP_sf.
DR   SUPFAM; SSF57959; SSF57959; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..650
FT                   /note="Probable basic-leucine zipper transcription factor
FT                   K"
FT                   /id="PRO_0000383603"
FT   DOMAIN          305..368
FT                   /note="bZIP"
FT   REGION          109..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          242..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..327
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000250"
FT   REGION          330..337
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000250"
FT   REGION          452..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          37..180
FT                   /evidence="ECO:0000255"
FT   COILED          259..286
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        452..466
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   650 AA;  76847 MW;  2D248B482DB2AB24 CRC64;
     MEESNNFLLS PDSIWSQLLE NSYALNEINC FQSFGTIDNN NNNYSNNNKN GNEELSQPTE
     IQQQLQNYQE LQQQKYQERQ QQYQTQYQQP YIEPIFEIVV TQQDQQELIP QQQQQEQDQQ
     EDQDQEQEQE LQQQQQQLQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQKQQ KQQKQQQQEQ
     PSIIKEQDQE QKKIIQEQLC EKSIQTLENH FFNTNTPKLD HQILSNYSEF FKINQPITDI
     PTTLNTNLQS DNNNNNNNNN NNNNNNNNNN NNNNNNNNLL NEKQIESTSK IKRINLGYDI
     TKITFNKIEK GKRNQTESSK NFRERKKEYI KDIELKLKEL TIENDKLKKE NDTLKKIGIE
     IMRSEPESIN MIMECKKIIK KLEKALIDND ERSLIYLLYL YHSETSKRYS LTEIEVDKII
     NPYSQLKLKL AGYIQNPTTE ILDIFGGNNN NNNNNNNNNN NNNNNNDNDD DNEEEEISWF
     KKYKKEANLT IEQSNKLDLL RDYHCLKFEL LLKERRELDR DIKKLYNGIA LSGFDLTPRS
     LANWDIDKQI ETTNKLNLLK IKIISSLNLN LDTFSSISSI LSPKQEALLL VRAHLFGSNK
     KNPHIEILNN VWTGLISKSS SPSFFEIAKL LKEMSDSANA KIMEDYLYKK