ID   BZPM_DICDI              Reviewed;         588 AA.
AC   Q54T17;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable basic-leucine zipper transcription factor M;
GN   Name=bzpM; ORFNames=DDB_G0282047;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=16410410; DOI=10.1242/dev.02240;
RA   Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT   "bZIP transcription factor interactions regulate DIF responses in
RT   Dictyostelium.";
RL   Development 133:449-458(2006).
CC   -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR   EMBL; AAFI02000044; EAL66445.1; -; Genomic_DNA.
DR   RefSeq; XP_640434.1; XM_635342.1.
DR   AlphaFoldDB; Q54T17; -.
DR   PaxDb; Q54T17; -.
DR   EnsemblProtists; EAL66445; EAL66445; DDB_G0282047.
DR   GeneID; 8623389; -.
DR   KEGG; ddi:DDB_G0282047; -.
DR   dictyBase; DDB_G0282047; bzpM.
DR   HOGENOM; CLU_421769_0_0_1; -.
DR   PhylomeDB; Q54T17; -.
DR   PRO; PR:Q54T17; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   Pfam; PF07716; bZIP_2; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..588
FT                   /note="Probable basic-leucine zipper transcription factor
FT                   M"
FT                   /id="PRO_0000383604"
FT   DOMAIN          263..326
FT                   /note="bZIP"
FT   REGION          221..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..289
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000250"
FT   REGION          291..312
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000250"
FT   COILED          127..157
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        221..242
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   588 AA;  69116 MW;  ADE97B9DBE7A19E9 CRC64;
     MEESNNNNFL FSPDYIWSQL LENNNNNYNN NYNNINNSIN ENLLNELNSF QNTGVFDLDT
     NIEQQQQQQP TEIQQQLQNY QEFQQKKYQE RQEQYQIQYQ QSYIEPLNFN ETYNNETYCN
     IIPQPPQVEQ QQEQEQEQEQ QQKQQQQQYI EKQIQEIIKI PEKRQTLNQI PIEMMQHNFF
     NTPKLDQQLL SNYSDFFKTN PILPTTTTTT TTTAITIDQQ QQNHIDNQSL NNSNTKTSKN
     QQKDNNLPKK KNLSYDITKI TFNNNNIEKK RDQTESSKNF REKKKEYVKE IESKILALTL
     ENDKLKKEND SLKTINGSNL MRPEPESINM IMECKKIIKK LEKALIDNDE RSLIYLLYHY
     HSETSKRYSL VEIEVDKIAN PYSQIKLKLA GYIQNPTTLD IFDGNFNNNN NNNGNKEEEE
     EISWFIKYKN EANLTIEQSN KLDLLRNQHG LIFETLLKER KQLDNEILKV FNEIIIASYD
     GSNANLISDK GFELKSKLKS LKMKIISSLN LNLDTFSSIS SILLPKQEAL LLVRAHLFGS
     SKLNPQMDFL NNVWTNIISS NSSCSVFEIL NSLKEFSDLE NLELNKNS