BZPN_DICDI
ID BZPN_DICDI Reviewed; 999 AA.
AC Q54LU5;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Probable basic-leucine zipper transcription factor N;
GN Name=bzpN; ORFNames=DDB_G0286411;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000085; EAL64230.1; -; Genomic_DNA.
DR RefSeq; XP_637735.1; XM_632643.1.
DR AlphaFoldDB; Q54LU5; -.
DR SMR; Q54LU5; -.
DR STRING; 44689.DDB0220085; -.
DR PaxDb; Q54LU5; -.
DR PRIDE; Q54LU5; -.
DR EnsemblProtists; EAL64230; EAL64230; DDB_G0286411.
DR GeneID; 8625600; -.
DR KEGG; ddi:DDB_G0286411; -.
DR dictyBase; DDB_G0286411; bzpN.
DR HOGENOM; CLU_300047_0_0_1; -.
DR InParanoid; Q54LU5; -.
DR OMA; IVNPCTQ; -.
DR PRO; PR:Q54LU5; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0031410; C:cytoplasmic vesicle; IDA:dictyBase.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:1903665; P:negative regulation of asexual reproduction; IMP:dictyBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..999
FT /note="Probable basic-leucine zipper transcription factor
FT N"
FT /id="PRO_0000383600"
FT DOMAIN 601..664
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 1..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..632
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 636..643
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 665..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 148..198
FT /evidence="ECO:0000255"
FT COILED 232..282
FT /evidence="ECO:0000255"
FT COILED 423..451
FT /evidence="ECO:0000255"
FT COILED 921..950
FT /evidence="ECO:0000255"
FT COMPBIAS 450..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..526
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 113862 MW; 7E00D3B71BEC046E CRC64;
MYQSIPQQGN YIYNGNNNFF PQQQPQQQQY LNNSNNNNNN NNNNNNNNNN INNNNNNFQQ
SYNNGNNNNY NNNNGYQQQT SSYDMYGNNV NINNNNNNNV NINSQNNVNN NNNNNNNNNN
GNINNNMLMA TSSALNNIVK VTNGYQQQQQ QQLLQQTTQQ QLQQQQQLLQ QQQQQIQQQQ
AALQLQLEQQ QQQKMVLMFG DEPMGYLPFS EDKNLMLLSA LNTNVDGGSF YGIQQQQQQQ
QLQQQQLQQQ QQLQQQQQQL QQQQIQQQQI QQQQQQQQQQ ISPIQESASP YYSTPIQSNT
MLSIPSSPGI PSSIPQLNNS NNINNNSNNN NNNNNNNNNN NINYNSNMAS NFISQHSNNG
SNTSSPVPQT TYLQNSGGNF NAYNGSNTNS PITPSSYLQP TTSQDQVIPQ QLSPNHDQNQ
QIIQQQQKIL QQQQQQQLLL QQQIQQQQQQ QLHQPQSPQL PQSPQQSPQQ SPQQLQPQQS
PQQPQQQPQQ QPQQLQQTQQ KTVQRPPIIQ PTTIQPQSPQ PPQQPQQKQP TINSSITPIQ
PIQQMIQQLT QNSSTKSTSK ASNIPATTAA CPKVDLLPNK SPISSYILPH DFEETLAHLS
EKQKTRRRAS QNLASRNYRQ RKKQYVNEVE DRLDDIVQEN ERLKKELYDS KKILKKLLHE
NNILKSGGQL PNKSDIPGCT GSEDEDEDDF DQFDQQQQDG SADPSTPVVE TEPDISVLVD
RLQVDMSITT QDDLTTTLKQ FYSTLKNRQD LYINQIKQIV NPCTQAKLAL LDGEISPAQS
CPFEDPSEKQ HSDPNSSPIG DMPSPYEQLE PTKWWSNFCN EANINPEQEN RVRQLRQESN
LRHKKIIKER THLNREIREY YHSKVFNGTV NNGGNTKSKK TAASTSTTTT TTSTSTTTTT
TTTISTDVDI SNNISSPVQS HLVQLSGLLD KLKENIDHEN ETLIQTYEKL GFILSPFQEA
LFITKIYNNI FSESSYSNIQ MLHGIKDAIL YSYVDPTYT
