ID   BZPO_DICDI              Reviewed;         716 AA.
AC   Q54GH0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable basic-leucine zipper transcription factor O;
GN   Name=bzpO; ORFNames=DDB_G0290169;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=16410410; DOI=10.1242/dev.02240;
RA   Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT   "bZIP transcription factor interactions regulate DIF responses in
RT   Dictyostelium.";
RL   Development 133:449-458(2006).
CC   -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000158; EAL62356.1; -; Genomic_DNA.
DR   RefSeq; XP_635858.1; XM_630766.1.
DR   AlphaFoldDB; Q54GH0; -.
DR   SMR; Q54GH0; -.
DR   STRING; 44689.DDB0216391; -.
DR   PaxDb; Q54GH0; -.
DR   EnsemblProtists; EAL62356; EAL62356; DDB_G0290169.
DR   GeneID; 8627514; -.
DR   KEGG; ddi:DDB_G0290169; -.
DR   dictyBase; DDB_G0290169; bzpO.
DR   HOGENOM; CLU_386090_0_0_1; -.
DR   InParanoid; Q54GH0; -.
DR   OMA; IEERYSH; -.
DR   PRO; PR:Q54GH0; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..716
FT                   /note="Probable basic-leucine zipper transcription factor
FT                   O"
FT                   /id="PRO_0000383605"
FT   DOMAIN          381..444
FT                   /note="bZIP"
FT   REGION          173..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..403
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000250"
FT   REGION          406..413
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000250"
FT   COILED          20..142
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   716 AA;  83397 MW;  792401E434B15A77 CRC64;
     MDGYQNFLPI PPENNTWLLL LDDFSQLQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
     QQQQQQQQQQ QQFPQQYTND GINVQSIESN NYLNNNNFNF NERLESLQKQ QQEQQTQIQQ
     QLQNYQQQYQ DQYQQRQQQY QDQYQKPYEL PSQYIDQCNQ IFSNYNNNNN ITSINYNMNN
     NNNSNNSNNN SNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNKTTDN INNVNSINNL
     NNINLGANNV NNNVNSNVVS NVNNNAISQN KPIFPPFNDN PINIQQQQQQ QQQQECYKIP
     QYKISLDNTN NPIITPTITP TLTTFPTITP TLITPTTIAP ITPTPTPTPI LTTTTTKTTK
     INLEETNEKT KIINETKKQE KSTESIKKMN QNKASRNYRQ KKKDYIKEIE DKLSLLEMEN
     SKIQKENQTL RKTGSVDLMK PSNDIMKMMT DCKTITNQLK LSLERNDDRS LIYLLHQYHR
     VIEERYSHIE YEAEKVANPY VQLRLSIVGY TPGQFCPFVL NIFNDNNDDG DNQKVTNDHN
     WYNTFKKEAN ITPEQSNKLD SIRFQHTKVS ASMFKEIQML DLEIKSFFYK FIFSYPSDPL
     SSLNPTELVY NSTTTTPIDS YSLPAIDKQL ELAGKLESLK NKLTLNGGLM LDTFSSISSL
     LTPRQEAIFL VGVDPYAFIN FSHFDIINDV WSNIINKPFS GPVHMAQSLN KMFNHS