BZPP_DICDI
ID BZPP_DICDI Reviewed; 831 AA.
AC Q54G94;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Probable basic-leucine zipper transcription factor P;
GN Name=bzpP; ORFNames=DDB_G0290303;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000162; EAL62278.1; -; Genomic_DNA.
DR RefSeq; XP_635789.1; XM_630697.1.
DR AlphaFoldDB; Q54G94; -.
DR SMR; Q54G94; -.
DR STRING; 44689.DDB0220088; -.
DR PaxDb; Q54G94; -.
DR EnsemblProtists; EAL62278; EAL62278; DDB_G0290303.
DR GeneID; 8627595; -.
DR KEGG; ddi:DDB_G0290303; -.
DR dictyBase; DDB_G0290303; bzpP.
DR HOGENOM; CLU_341442_0_0_1; -.
DR InParanoid; Q54G94; -.
DR PRO; PR:Q54G94; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..831
FT /note="Probable basic-leucine zipper transcription factor
FT P"
FT /id="PRO_0000383601"
FT DOMAIN 151..214
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..173
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 176..183
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 469..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 101..141
FT /evidence="ECO:0000255"
FT COILED 601..664
FT /evidence="ECO:0000255"
FT COMPBIAS 54..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 831 AA; 94391 MW; AB0551320250C50D CRC64;
MNHRIEDITS NPSSPSPNSP FSSPQVSLQP SIIQNGLNSN NSLLNGNNFN LNGNITSSPS
TSSSPPISTT TTTTTTTTTT ATAKKTNSKE KKKTTNKDNN NNNNNNNSNN QQQQQQQQQQ
QQQQQQQQQY EEEDDDEEDE GGDDNTKVGK GEKMKARRTN QNIASRNYRQ RKKVYIKEME
DKINSLTLEN DSLKKDLYKI GNNPLELLKF SQEVVFLMTQ IRRLVFQIDQ ALRNSEPDSS
IKSLLNTWQS TMDQASSINE REIERFVHPY TQAKLTVMGY KPHTNPWTDF IKTPGQEDWW
TKYAEKANLS SDQLEQINNL WLRFDEEERV LQKELTDLDE YIKKFFLTKI IIMPDTEKLN
DIISSCLPIP ENHDGDILQT SEVLEFIYNL EKLKQKFIKV QRLTWDTSKQ MSKYLTVRQE
AFLLVLVHSN TKYIHTNMDM TNNLWNQLNH SALSKTPSTY LLGGVHSSSS SSSSSSSSMS
SSTSRILNNH GIPTPLSSSN SSPSSLSASS SIGESIHSYS QLPNVVQPIQ TQPSSMFTPL
PGAKPLKNQQ PIDDLFFGTI PLSQVPLSFQ QNSNMALFSN YRNFTQQQAQ QQQQQQQQQH
AQQHAQQQAQ QQAHLQAQIQ AQIMQQAQQI HQVQQAQQAS QQAAQQAAQQ AAAQQAAQQQ
AAQQQSPIQT QLSPPQHITP QHTPQQHIQQ QQQHQNYQGT EPHLLGEFMF FNSIDATNSN
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN STPIDQLNEY RPDYNNNNTN KILPNIIQSL
SASSNNSLFS HQHQQQNSQS PTLPPSQNDS VQFHFYQPIH QNNQNNQNHN N
