BZPQ_DICDI
ID BZPQ_DICDI Reviewed; 976 AA.
AC Q54IJ9;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Probable basic-leucine zipper transcription factor Q;
GN Name=bzpQ; ORFNames=DDB_G0288705;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000120; EAL63084.1; -; Genomic_DNA.
DR RefSeq; XP_636587.1; XM_631495.1.
DR AlphaFoldDB; Q54IJ9; -.
DR PaxDb; Q54IJ9; -.
DR EnsemblProtists; EAL63084; EAL63084; DDB_G0288705.
DR GeneID; 8626761; -.
DR KEGG; ddi:DDB_G0288705; -.
DR dictyBase; DDB_G0288705; bzpQ.
DR eggNOG; ENOG502S8CW; Eukaryota.
DR HOGENOM; CLU_304500_0_0_1; -.
DR InParanoid; Q54IJ9; -.
DR OMA; NYRQRRK; -.
DR PRO; PR:Q54IJ9; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..976
FT /note="Probable basic-leucine zipper transcription factor
FT Q"
FT /id="PRO_0000384411"
FT DOMAIN 504..567
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 104..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..507
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 509..516
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 855..957
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 57..110
FT /evidence="ECO:0000255"
FT COILED 136..287
FT /evidence="ECO:0000255"
FT COMPBIAS 374..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..944
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 112308 MW; 0968AB00D575A275 CRC64;
MEEFENFFSQ LIPAPDQDIW LLAAQQTPQN NDGVSTSGIP IGWSLQNLAA STNNIAAIDS
NPQIREQLQQ LQQQQQQQQT QIQQQLQSYQ QQQQQHYQQR QQQYQQQYQQ PYTTPSPPDQ
IDYNQQLSPQ QQQQQQQQQQ QQQQQQQQQP QLQQQNNTIS QQQQQQNLNF QVQFLQQQQQ
HQQQLQQQQE QFQHQQLQHQ QQQYFIKQQL QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
QQQQQNQHLS PILSPLPPIQ QLQQYQQQQQ QQQQQQQQQQ QQQQQQQPQQ QSINIGSSNT
PLQHQAMLQA QSLMDSINTK QPPIPPTLQS PTQHQFLNTP VLDQHILSSI RPSYSQVTKA
NISTLPTEIT NSLTNFNGTN NSTPNFEDLT GGKLSSNNIK NTATPLSSPP STKNGKQKQP
KNNNNNNNSS NNNNNNNQTT TQQKQSKNNN SYGNNSNNNN NNNNFNNNKL KKQNDSTTTP
TITSPNMTSP IDSNGDFDLL DEDEKKKSIS RINQNLASRN YRQRRKEYIK EIESKMAALT
FENHQLKKEN ESLKETGGVE VMRPEPELIT MVVEGKQIII QLSQALKKND DRSLIYLLHL
YHCAIAKRYS IVEREVEKIV HPYTQSKLAA MGYIPKSDKM FLNCIAGPAA DSWFQLFKNE
AEITLEQSNK LEALRTQHGK IDSALLQERQ ELDLDIKKFY YTKILVLPNN PLIIGDIPAQ
PYNGELSQSP ISNSPLEISQ LLDFAGKLES LKKNFILHRN LMLDTLASLS SILTPRQEAM
LLVRVHFYTS YDFSHMELLK DVWTNIVSSK SITGPLNISE ALKKLSDTTN THHSIENIVK
PPQFHQYTPK QLKFENQSNN FGNNNGSKSK NIENNLNNSV NNNNNNNNNN NNNNNNNNNN
NNNNNNNNNN NNNSNSNNNN NVNSNSSNVN SNNNNFNNAP QMVLNPPSAD AIPYPSTTQL
DKRFQWVSYP SAPPPN
